Graham FL - Search Results

1

Use of a liver-specific promoter reduces immune response to the transgene in adenoviral vectors.

Pastore L, Morral N, Zhou H, Garcia R, Parks RJ, Kochanek S, Graham FL, Lee B, Beaudet AL. Pastore L, et al. Among authors: graham fl. Hum Gene Ther. 1999 Jul 20;10(11):1773-81. doi: 10.1089/10430349950017455. Hum Gene Ther. 1999. PMID: 10446917

2

Use of helper-dependent adenoviral vectors of alternative serotypes permits repeat vector administration.

Parks R, Evelegh C, Graham F. Parks R, et al. Gene Ther. 1999 Sep;6(9):1565-73. doi: 10.1038/sj.gt.3300995. Gene Ther. 1999. PMID: 10490766

3

Genomic DNA transfer with a high-capacity adenovirus vector results in improved in vivo gene expression and decreased toxicity.

Schiedner G, Morral N, Parks RJ, Wu Y, Koopmans SC, Langston C, Graham FL, Beaudet AL, Kochanek S. Schiedner G, et al. Among authors: graham fl. Nat Genet. 1998 Feb;18(2):180-3. doi: 10.1038/ng0298-180. Nat Genet. 1998. PMID: 9462752

4

High doses of a helper-dependent adenoviral vector yield supraphysiological levels of alpha1-antitrypsin with negligible toxicity.

Morral N, Parks RJ, Zhou H, Langston C, Schiedner G, Quinones J, Graham FL, Kochanek S, Beaudet AL. Morral N, et al. Among authors: graham fl. Hum Gene Ther. 1998 Dec 10;9(18):2709-16. doi: 10.1089/hum.1998.9.18-2709. Hum Gene Ther. 1998. PMID: 9874269

5

Administration of helper-dependent adenoviral vectors and sequential delivery of different vector serotype for long-term liver-directed gene transfer in baboons.

Morral N, O'Neal W, Rice K, Leland M, Kaplan J, Piedra PA, Zhou H, Parks RJ, Velji R, Aguilar-Córdova E, Wadsworth S, Graham FL, Kochanek S, Carey KD, Beaudet AL. Morral N, et al. Among authors: graham fl. Proc Natl Acad Sci U S A. 1999 Oct 26;96(22):12816-21. doi: 10.1073/pnas.96.22.12816. Proc Natl Acad Sci U S A. 1999. PMID: 10536005 Free PMC article.

6

Toxicity associated with repeated administration of first-generation adenovirus vectors does not occur with a helper-dependent vector.

O'Neal WK, Zhou H, Morral N, Langston C, Parks RJ, Graham FL, Kochanek S, Beaudet AL. O'Neal WK, et al. Among authors: graham fl. Mol Med. 2000 Mar;6(3):179-95. Mol Med. 2000. PMID: 10965494 Free PMC article.

7

Development of a size-restricted pIX-deleted helper virus for amplification of helper-dependent adenovirus vectors.

Sargent KL, Ng P, Evelegh C, Graham FL, Parks RJ. Sargent KL, et al. Among authors: graham fl. Gene Ther. 2004 Mar;11(6):504-11. doi: 10.1038/sj.gt.3302107. Gene Ther. 2004. PMID: 14999222

8

An adenoviral vector deleted for all viral coding sequences results in enhanced safety and extended expression of a leptin transgene.

Morsy MA, Gu M, Motzel S, Zhao J, Lin J, Su Q, Allen H, Franlin L, Parks RJ, Graham FL, Kochanek S, Bett AJ, Caskey CT. Morsy MA, et al. Among authors: graham fl. Proc Natl Acad Sci U S A. 1998 Jul 7;95(14):7866-71. doi: 10.1073/pnas.95.14.7866. Proc Natl Acad Sci U S A. 1998. PMID: 9653106 Free PMC article.

9

A high-efficiency Cre/loxP-based system for construction of adenoviral vectors.

Ng P, Parks RJ, Cummings DT, Evelegh CM, Sankar U, Graham FL. Ng P, et al. Among authors: graham fl. Hum Gene Ther. 1999 Nov 1;10(16):2667-72. doi: 10.1089/10430349950016708. Hum Gene Ther. 1999. PMID: 10566894

10

An enhanced system for construction of adenoviral vectors by the two-plasmid rescue method.

Ng P, Parks RJ, Cummings DT, Evelegh CM, Graham FL. Ng P, et al. Among authors: graham fl. Hum Gene Ther. 2000 Mar 20;11(5):693-9. doi: 10.1089/10430340050015590. Hum Gene Ther. 2000. PMID: 10757349

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