Kochanek S - Search Results

1

Use of a liver-specific promoter reduces immune response to the transgene in adenoviral vectors.

Pastore L, Morral N, Zhou H, Garcia R, Parks RJ, Kochanek S, Graham FL, Lee B, Beaudet AL. Pastore L, et al. Among authors: kochanek s. Hum Gene Ther. 1999 Jul 20;10(11):1773-81. doi: 10.1089/10430349950017455. Hum Gene Ther. 1999. PMID: 10446917

2

Genomic DNA transfer with a high-capacity adenovirus vector results in improved in vivo gene expression and decreased toxicity.

Schiedner G, Morral N, Parks RJ, Wu Y, Koopmans SC, Langston C, Graham FL, Beaudet AL, Kochanek S. Schiedner G, et al. Among authors: kochanek s. Nat Genet. 1998 Feb;18(2):180-3. doi: 10.1038/ng0298-180. Nat Genet. 1998. PMID: 9462752

3

High doses of a helper-dependent adenoviral vector yield supraphysiological levels of alpha1-antitrypsin with negligible toxicity.

Morral N, Parks RJ, Zhou H, Langston C, Schiedner G, Quinones J, Graham FL, Kochanek S, Beaudet AL. Morral N, et al. Among authors: kochanek s. Hum Gene Ther. 1998 Dec 10;9(18):2709-16. doi: 10.1089/hum.1998.9.18-2709. Hum Gene Ther. 1998. PMID: 9874269

4

Administration of helper-dependent adenoviral vectors and sequential delivery of different vector serotype for long-term liver-directed gene transfer in baboons.

Morral N, O'Neal W, Rice K, Leland M, Kaplan J, Piedra PA, Zhou H, Parks RJ, Velji R, Aguilar-Córdova E, Wadsworth S, Graham FL, Kochanek S, Carey KD, Beaudet AL. Morral N, et al. Among authors: kochanek s. Proc Natl Acad Sci U S A. 1999 Oct 26;96(22):12816-21. doi: 10.1073/pnas.96.22.12816. Proc Natl Acad Sci U S A. 1999. PMID: 10536005 Free PMC article.

5

Toxicity associated with repeated administration of first-generation adenovirus vectors does not occur with a helper-dependent vector.

O'Neal WK, Zhou H, Morral N, Langston C, Parks RJ, Graham FL, Kochanek S, Beaudet AL. O'Neal WK, et al. Among authors: kochanek s. Mol Med. 2000 Mar;6(3):179-95. Mol Med. 2000. PMID: 10965494 Free PMC article.

6

An adenoviral vector deleted for all viral coding sequences results in enhanced safety and extended expression of a leptin transgene.

Morsy MA, Gu M, Motzel S, Zhao J, Lin J, Su Q, Allen H, Franlin L, Parks RJ, Graham FL, Kochanek S, Bett AJ, Caskey CT. Morsy MA, et al. Among authors: kochanek s. Proc Natl Acad Sci U S A. 1998 Jul 7;95(14):7866-71. doi: 10.1073/pnas.95.14.7866. Proc Natl Acad Sci U S A. 1998. PMID: 9653106 Free PMC article.

7

Rescue, propagation, and partial purification of a helper virus-dependent adenovirus vector.

Mitani K, Graham FL, Caskey CT, Kochanek S. Mitani K, et al. Among authors: kochanek s. Proc Natl Acad Sci U S A. 1995 Apr 25;92(9):3854-8. doi: 10.1073/pnas.92.9.3854. Proc Natl Acad Sci U S A. 1995. PMID: 7731995 Free PMC article.

8

Targeting of high-capacity adenoviral vectors.

Biermann V, Volpers C, Hussmann S, Stock A, Kewes H, Schiedner G, Herrmann A, Kochanek S. Biermann V, et al. Among authors: kochanek s. Hum Gene Ther. 2001 Sep 20;12(14):1757-69. doi: 10.1089/104303401750476258. Hum Gene Ther. 2001. PMID: 11560769

9

Selective depletion or blockade of Kupffer cells leads to enhanced and prolonged hepatic transgene expression using high-capacity adenoviral vectors.

Schiedner G, Hertel S, Johnston M, Dries V, van Rooijen N, Kochanek S. Schiedner G, et al. Among authors: kochanek s. Mol Ther. 2003 Jan;7(1):35-43. doi: 10.1016/s1525-0016(02)00017-5. Mol Ther. 2003. PMID: 12573616 Free article.

10

High-capacity adenoviral vectors for gene transfer and somatic gene therapy.

Kochanek S. Kochanek S. Hum Gene Ther. 1999 Oct 10;10(15):2451-9. doi: 10.1089/10430349950016807. Hum Gene Ther. 1999. PMID: 10543611 Review.

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