Muñoz-Torrero D - Search Results

1

Synthesis, in vitro pharmacology, and molecular modeling of very potent tacrine-huperzine A hybrids as acetylcholinesterase inhibitors of potential interest for the treatment of Alzheimer's disease.

Camps P, El Achab R, Görbig DM, Morral J, Muñoz-Torrero D, Badia A, Eladi Baños J, Vivas NM, Barril X, Orozco M, Luque FJ. Camps P, et al. J Med Chem. 1999 Aug 26;42(17):3227-42. doi: 10.1021/jm980620z. J Med Chem. 1999. PMID: 10464010

2

Chlorpyrifos Oxon Activates Glutamate and Lysine for Protein Cross-linking.

Muñoz-Torrero D, Schopfer LM, Lockridge O. Muñoz-Torrero D, et al. Chem Res Toxicol. 2023 Jan 16;36(1):112-121. doi: 10.1021/acs.chemrestox.2c00333. Epub 2023 Jan 4. Chem Res Toxicol. 2023. PMID: 36598934 Free PMC article.

3

Synthesis and evaluation of tacrine-huperzine A hybrids as acetylcholinesterase inhibitors of potential interest for the treatment of Alzheimer's disease.

Badia A, Baños JE, Camps P, Contreras J, Görbig DM, Muñoz-Torrero D, Simón M, Vivas NM. Badia A, et al. Bioorg Med Chem. 1998 Apr;6(4):427-40. doi: 10.1016/s0968-0896(98)00015-7. Bioorg Med Chem. 1998. PMID: 9597187

4

Huprine X is a novel high-affinity inhibitor of acetylcholinesterase that is of interest for treatment of Alzheimer's disease.

Camps P, Cusack B, Mallender WD, El Achab RE, Morral J, Muñoz-Torrero D, Rosenberry TL. Camps P, et al. Mol Pharmacol. 2000 Feb;57(2):409-17. Mol Pharmacol. 2000. PMID: 10648652

5

New tacrine-huperzine A hybrids (huprines): highly potent tight-binding acetylcholinesterase inhibitors of interest for the treatment of Alzheimer's disease.

Camps P, El Achab R, Morral J, Muñoz-Torrero D, Badia A, Baños JE, Vivas NM, Barril X, Orozco M, Luque FJ. Camps P, et al. J Med Chem. 2000 Nov 30;43(24):4657-66. doi: 10.1021/jm000980y. J Med Chem. 2000. PMID: 11101357

6

The pharmacology of novel acetylcholinesterase inhibitors, (+/-)-huprines Y and X, on the Torpedo electric organ.

Ros E, Aleu J, Gómez de Aranda I, Muñoz-Torrero D, Camps P, Badia A, Marsal J, Solsona C. Ros E, et al. Eur J Pharmacol. 2001 Jun 8;421(2):77-84. doi: 10.1016/s0014-2999(01)01028-7. Eur J Pharmacol. 2001. PMID: 11399262

7

Synthesis, in vitro pharmacology, and molecular modeling of syn-huprines as acetylcholinesterase inhibitors.

Camps P, Gómez E, Muñoz-Torrero D, Badia A, Vivas NM, Barril X, Orozco M, Luque FJ. Camps P, et al. J Med Chem. 2001 Dec 20;44(26):4733-6. doi: 10.1021/jm010949b. J Med Chem. 2001. PMID: 11741490

8

3D structure of Torpedo californica acetylcholinesterase complexed with huprine X at 2.1 A resolution: kinetic and molecular dynamic correlates.

Dvir H, Wong DM, Harel M, Barril X, Orozco M, Luque FJ, Muñoz-Torrero D, Camps P, Rosenberry TL, Silman I, Sussman JL. Dvir H, et al. Biochemistry. 2002 Mar 5;41(9):2970-81. doi: 10.1021/bi011652i. Biochemistry. 2002. PMID: 11863435

9

Cholinergic drugs in pharmacotherapy of Alzheimer's disease.

Camps P, Muñoz-Torrero D. Camps P, et al. Mini Rev Med Chem. 2002 Feb;2(1):11-25. doi: 10.2174/1389557023406638. Mini Rev Med Chem. 2002. PMID: 12369954 Review.

10

Tacrine-huperzine A hybrids (huprines): a new class of highly potent and selective acetylcholinesterase inhibitors of interest for the treatment of Alzheimer's disease.

Camps P, Muñoz-Torrero D. Camps P, et al. Mini Rev Med Chem. 2001 Jul;1(2):163-74. doi: 10.2174/1389557013406972. Mini Rev Med Chem. 2001. PMID: 12369981 Review.

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