Woltering T - Search Results

1

Synthesis of heterocyclic enol ethers and their use as group 2 metabotropic glutamate receptor antagonists.

Kolczewski S, Adam G, Stadler H, Mutel V, Wichmann J, Woltering T. Kolczewski S, et al. Among authors: woltering t. Bioorg Med Chem Lett. 1999 Aug 2;9(15):2173-6. doi: 10.1016/s0960-894x(99)00346-7. Bioorg Med Chem Lett. 1999. PMID: 10465539

2

Synthesis and characterization of 8-ethynyl-1,3-dihydro-benzo[b][1,4]diazepin-2-one derivatives: new potent non-competitive metabotropic glutamate receptor 2/3 antagonists. Part 1.

Woltering TJ, Adam G, Alanine A, Wichmann J, Knoflach F, Mutel V, Gatti S. Woltering TJ, et al. Bioorg Med Chem Lett. 2007 Dec 15;17(24):6811-5. doi: 10.1016/j.bmcl.2007.10.026. Epub 2007 Oct 17. Bioorg Med Chem Lett. 2007. PMID: 17964783

3

Synthesis and characterization of 8-ethynyl-1,3-dihydro-benzo[b][1,4]diazepin-2-one derivatives: part 2. New potent non-competitive metabotropic glutamate receptor 2/3 antagonists.

Woltering TJ, Adam G, Wichmann J, Goetschi E, Kew JN, Knoflach F, Mutel V, Gatti S. Woltering TJ, et al. Bioorg Med Chem Lett. 2008 Feb 1;18(3):1091-5. doi: 10.1016/j.bmcl.2007.12.005. Epub 2007 Dec 8. Bioorg Med Chem Lett. 2008. PMID: 18096387

4

Synthesis and characterization of 1,3-dihydro-benzo[b][1,4]diazepin-2-one derivatives: Part 3. New potent non-competitive metabotropic glutamate receptor 2/3 antagonists.

Woltering TJ, Wichmann J, Goetschi E, Adam G, Kew JN, Knoflach F, Ballard TM, Huwyler J, Mutel V, Gatti S. Woltering TJ, et al. Bioorg Med Chem Lett. 2008 Apr 15;18(8):2725-9. doi: 10.1016/j.bmcl.2008.02.076. Epub 2008 Mar 5. Bioorg Med Chem Lett. 2008. PMID: 18374569

5

Synthesis and characterization of 1,3-dihydro-benzo[b][1,4]diazepin-2-one derivatives: Part 4. In vivo active potent and selective non-competitive metabotropic glutamate receptor 2/3 antagonists.

Woltering TJ, Wichmann J, Goetschi E, Knoflach F, Ballard TM, Huwyler J, Gatti S. Woltering TJ, et al. Bioorg Med Chem Lett. 2010 Dec 1;20(23):6969-74. doi: 10.1016/j.bmcl.2010.09.125. Epub 2010 Oct 21. Bioorg Med Chem Lett. 2010. PMID: 20971004

6

In vitro binding characteristics of a new selective group II metabotropic glutamate receptor radioligand, [3H]LY354740, in rat brain.

Schaffhauser H, Richards JG, Cartmell J, Chaboz S, Kemp JA, Klingelschmidt A, Messer J, Stadler H, Woltering T, Mutel V. Schaffhauser H, et al. Among authors: woltering t. Mol Pharmacol. 1998 Feb;53(2):228-33. Mol Pharmacol. 1998. PMID: 9463480

7

Structure-activity relationships of substituted 5H-thiazolo[3,2-a]pyrimidines as group 2 metabotropic glutamate receptor antagonists.

Wichmann J, Adam G, Kolczewski S, Mutel V, Woltering T. Wichmann J, et al. Among authors: woltering t. Bioorg Med Chem Lett. 1999 Jun 7;9(11):1573-6. doi: 10.1016/s0960-894x(99)00227-9. Bioorg Med Chem Lett. 1999. PMID: 10386938

8

Characterization of [(3)H]-LY354740 binding to rat mGlu2 and mGlu3 receptors expressed in CHO cells using semliki forest virus vectors.

Schweitzer C, Kratzeisen C, Adam G, Lundstrom K, Malherbe P, Ohresser S, Stadler H, Wichmann J, Woltering T, Mutel V. Schweitzer C, et al. Among authors: woltering t. Neuropharmacology. 2000 Jul 24;39(10):1700-6. doi: 10.1016/s0028-3908(99)00265-8. Neuropharmacology. 2000. PMID: 10884552

9

Pharmacological properties of native metabotropic glutamate receptors in freshly dissociated Golgi cells of the rat cerebellum.

Knoflach F, Woltering T, Adam G, Mutel V, Kemp JA. Knoflach F, et al. Among authors: woltering t. Neuropharmacology. 2001;40(2):163-9. doi: 10.1016/s0028-3908(00)00152-0. Neuropharmacology. 2001. PMID: 11114394

10

Structural determinants of allosteric antagonism at metabotropic glutamate receptor 2: mechanistic studies with new potent negative allosteric modulators.

Lundström L, Bissantz C, Beck J, Wettstein JG, Woltering TJ, Wichmann J, Gatti S. Lundström L, et al. Among authors: woltering tj. Br J Pharmacol. 2011 Sep;164(2b):521-37. doi: 10.1111/j.1476-5381.2011.01409.x. Br J Pharmacol. 2011. PMID: 21470207 Free PMC article.

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