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Page 1
Sulfonamidopyrrolidinone factor Xa inhibitors: potency and selectivity enhancements via P-1 and P-4 optimization.
Choi-Sledeski YM, McGarry DG, Green DM, Mason HJ, Becker MR, Davis RS, Ewing WR, Dankulich WP, Manetta VE, Morris RL, Spada AP, Cheney DL, Brown KD, Colussi DJ, Chu V, Heran CL, Morgan SR, Bentley RG, Leadley RJ, Maignan S, Guilloteau JP, Dunwiddie CT, Pauls HW. Choi-Sledeski YM, et al. Among authors: mcgarry dg. J Med Chem. 1999 Sep 9;42(18):3572-87. doi: 10.1021/jm990041+. J Med Chem. 1999. PMID: 10479289
2-Substituted-4-methoxybenzimidazole-based PDE4 inhibitors.
Regan J, Bruno J, McGarry D, Poli G, Hanney B, Bower S, Travis J, Sweeney D, Miller B, Souness J, Djuric S. Regan J, et al. Bioorg Med Chem Lett. 1998 Oct 6;8(19):2737-42. doi: 10.1016/s0960-894x(98)00497-1. Bioorg Med Chem Lett. 1998. PMID: 9873613
Benzofuran based PDE4 inhibitors.
McGarry DG, Regan JR, Volz FA, Hulme C, Moriarty KJ, Djuric SW, Souness JE, Miller BE, Travis JJ, Sweeney DM. McGarry DG, et al. Bioorg Med Chem. 1999 Jun;7(6):1131-9. doi: 10.1016/s0968-0896(99)00038-3. Bioorg Med Chem. 1999. PMID: 10428384
Discovery of Taniborbactam (VNRX-5133): A Broad-Spectrum Serine- and Metallo-β-lactamase Inhibitor for Carbapenem-Resistant Bacterial Infections.
Liu B, Trout REL, Chu GH, McGarry D, Jackson RW, Hamrick JC, Daigle DM, Cusick SM, Pozzi C, De Luca F, Benvenuti M, Mangani S, Docquier JD, Weiss WJ, Pevear DC, Xerri L, Burns CJ. Liu B, et al. J Med Chem. 2020 Mar 26;63(6):2789-2801. doi: 10.1021/acs.jmedchem.9b01518. Epub 2019 Dec 16. J Med Chem. 2020. PMID: 31765155 Free PMC article.