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A loss of function mutation of presenilin-2 interferes with amyloid beta-peptide production and notch signaling.
J Biol Chem. 1999 Oct 1;274(40):28669-73. doi: 10.1074/jbc.274.40.28669.
J Biol Chem. 1999.
PMID: 10497236
Free article.
The biological and pathological function of the presenilin-1 Deltaexon 9 mutation is independent of its defect to undergo proteolytic processing.
Steiner H, Romig H, Grim MG, Philipp U, Pesold B, Citron M, Baumeister R, Haass C.
Steiner H, et al. Among authors: grim mg.
J Biol Chem. 1999 Mar 19;274(12):7615-8. doi: 10.1074/jbc.274.12.7615.
J Biol Chem. 1999.
PMID: 10075646
Free article.
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Presenilin-1 differentially facilitates endoproteolysis of the beta-amyloid precursor protein and Notch.
Capell A, Steiner H, Romig H, Keck S, Baader M, Grim MG, Baumeister R, Haass C.
Capell A, et al. Among authors: grim mg.
Nat Cell Biol. 2000 Apr;2(4):205-11. doi: 10.1038/35008626.
Nat Cell Biol. 2000.
PMID: 10783238
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A pathogenic presenilin-1 deletion causes abberrant Abeta 42 production in the absence of congophilic amyloid plaques.
Steiner H, Revesz T, Neumann M, Romig H, Grim MG, Pesold B, Kretzschmar HA, Hardy J, Holton JL, Baumeister R, Houlden H, Haass C.
Steiner H, et al. Among authors: grim mg.
J Biol Chem. 2001 Mar 9;276(10):7233-9. doi: 10.1074/jbc.M007183200. Epub 2000 Nov 17.
J Biol Chem. 2001.
PMID: 11084029
Free article.
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The influence of endoproteolytic processing of familial Alzheimer's disease presenilin 2 on abeta42 amyloid peptide formation.
Jacobsen H, Reinhardt D, Brockhaus M, Bur D, Kocyba C, Kurt H, Grim MG, Baumeister R, Loetscher H.
Jacobsen H, et al. Among authors: grim mg.
J Biol Chem. 1999 Dec 3;274(49):35233-9. doi: 10.1074/jbc.274.49.35233.
J Biol Chem. 1999.
PMID: 10575009
Free article.
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Retention of a cis Golgi protein requires polar residues on one face of a predicted alpha-helix in the transmembrane domain.
Machamer CE, Grim MG, Esquela A, Chung SW, Rolls M, Ryan K, Swift AM.
Machamer CE, et al. Among authors: grim mg.
Mol Biol Cell. 1993 Jul;4(7):695-704. doi: 10.1091/mbc.4.7.695.
Mol Biol Cell. 1993.
PMID: 8400455
Free PMC article.
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Oxidative stress and AP-1 activity in tamoxifen-resistant breast tumors in vivo.
Schiff R, Reddy P, Ahotupa M, Coronado-Heinsohn E, Grim M, Hilsenbeck SG, Lawrence R, Deneke S, Herrera R, Chamness GC, Fuqua SA, Brown PH, Osborne CK.
Schiff R, et al.
J Natl Cancer Inst. 2000 Dec 6;92(23):1926-34. doi: 10.1093/jnci/92.23.1926.
J Natl Cancer Inst. 2000.
PMID: 11106684
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