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Page 1
Tumor eradication by wild-type p53-specific cytotoxic T lymphocytes.
Vierboom MP, Nijman HW, Offringa R, van der Voort EI, van Hall T, van den Broek L, Fleuren GJ, Kenemans P, Kast WM, Melief CJ. Vierboom MP, et al. Among authors: offringa r. J Exp Med. 1997 Aug 29;186(5):695-704. doi: 10.1084/jem.186.5.695. J Exp Med. 1997. PMID: 9271585 Free PMC article.
CD4 T cells and their role in antitumor immune responses.
Toes RE, Ossendorp F, Offringa R, Melief CJ. Toes RE, et al. Among authors: offringa r. J Exp Med. 1999 Mar 1;189(5):753-6. doi: 10.1084/jem.189.5.753. J Exp Med. 1999. PMID: 10049938 Free PMC article. No abstract available.
Expression of the serpin serine protease inhibitor 6 protects dendritic cells from cytotoxic T lymphocyte-induced apoptosis: differential modulation by T helper type 1 and type 2 cells.
Medema JP, Schuurhuis DH, Rea D, van Tongeren J, de Jong J, Bres SA, Laban S, Toes RE, Toebes M, Schumacher TN, Bladergroen BA, Ossendorp F, Kummer JA, Melief CJ, Offringa R. Medema JP, et al. Among authors: offringa r. J Exp Med. 2001 Sep 3;194(5):657-67. doi: 10.1084/jem.194.5.657. J Exp Med. 2001. PMID: 11535633 Free PMC article.
Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses.
Sutmuller RP, van Duivenvoorde LM, van Elsas A, Schumacher TN, Wildenberg ME, Allison JP, Toes RE, Offringa R, Melief CJ. Sutmuller RP, et al. Among authors: offringa r. J Exp Med. 2001 Sep 17;194(6):823-32. doi: 10.1084/jem.194.6.823. J Exp Med. 2001. PMID: 11560997 Free PMC article.
Blockade of the granzyme B/perforin pathway through overexpression of the serine protease inhibitor PI-9/SPI-6 constitutes a mechanism for immune escape by tumors.
Medema JP, de Jong J, Peltenburg LT, Verdegaal EM, Gorter A, Bres SA, Franken KL, Hahne M, Albar JP, Melief CJ, Offringa R. Medema JP, et al. Among authors: offringa r. Proc Natl Acad Sci U S A. 2001 Sep 25;98(20):11515-20. doi: 10.1073/pnas.201398198. Epub 2001 Sep 18. Proc Natl Acad Sci U S A. 2001. PMID: 11562487 Free PMC article.
Selective cytotoxic T-lymphocyte targeting of tumor immune escape variants.
van Hall T, Wolpert EZ, van Veelen P, Laban S, van der Veer M, Roseboom M, Bres S, Grufman P, de Ru A, Meiring H, de Jong A, Franken K, Teixeira A, Valentijn R, Drijfhout JW, Koning F, Camps M, Ossendorp F, Kärre K, Ljunggren HG, Melief CJ, Offringa R. van Hall T, et al. Among authors: offringa r. Nat Med. 2006 Apr;12(4):417-24. doi: 10.1038/nm1381. Epub 2006 Mar 19. Nat Med. 2006. PMID: 16550190
267 results