Chang KC - Search Results

1

Prevention of the expression of inducible nitric oxide synthase by a novel positive inotropic agent, YS 49, in rat vascular smooth muscle and RAW 264.7 macrophages.

Kang YJ, Koo EB, Lee YS, Yun-Choi HS, Chang KC. Kang YJ, et al. Among authors: chang kc. Br J Pharmacol. 1999 Sep;128(2):357-64. doi: 10.1038/sj.bjp.0702787. Br J Pharmacol. 1999. PMID: 10510445 Free PMC article.

2

Suppression of tumor necrosis factor-alpha and inducible nitric oxide synthase gene expression by THI 52, a new synthetic naphthyl-benzylisoquinoline alkaloid.

Kang YJ, Lee BK, Lee YS, Seo HG, Park MK, Kim HJ, Pyo HS, Chong WS, Jung HJ, Yun-Choi HS, Lee DH, Chang KC. Kang YJ, et al. Among authors: chang kc. Biochem Pharmacol. 2003 Feb 1;65(3):457-64. doi: 10.1016/s0006-2952(02)01549-6. Biochem Pharmacol. 2003. PMID: 12527339

3

A synthetic isoquinoline alkaloid, 1-(beta-naphthylmethyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline (YS 51), reduces inducible nitric oxide synthase expression and improves survival in a rodent model of endotoxic shock.

Kang YJ, Seo SJ, Yun-Choi HS, Lee DH, Kim YM, Chang KC. Kang YJ, et al. Among authors: chang kc. J Pharmacol Exp Ther. 2002 May;301(2):561-7. doi: 10.1124/jpet.301.2.561. J Pharmacol Exp Ther. 2002. PMID: 11961057

4

Induction of manganese-superoxide dismutase by YS 51, a synthetic 1-(beta-naphtylmethyl)6,7-dihydroxy- 1,2,3,4-tetrahydroisoquinoline alkaloid: implication for anti-inflammatory actions.

Seo HG, Kim HJ, Ko YS, Pyo HS, Kang YJ, Lee YS, Park MK, Yun-Choi HS, Chang KC. Seo HG, et al. Among authors: chang kc. Pharmacology. 2004 Jun;71(2):57-65. doi: 10.1159/000076941. Pharmacology. 2004. PMID: 15118344

5

Regulation of lipopolysaccharide-induced inducible nitric-oxide synthase expression through the nuclear factor-kappaB pathway and interferon-beta/tyrosine kinase 2/Janus tyrosine kinase 2-signal transducer and activator of transcription-1 signaling cascades by 2-naphthylethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline (THI 53), a new synthetic isoquinoline alkaloid.

Kim HJ, Tsoyi K, Heo JM, Kang YJ, Park MK, Lee YS, Lee JH, Seo HG, Yun-Choi HS, Chang KC. Kim HJ, et al. Among authors: chang kc. J Pharmacol Exp Ther. 2007 Feb;320(2):782-9. doi: 10.1124/jpet.106.112052. Epub 2006 Nov 15. J Pharmacol Exp Ther. 2007. PMID: 17108235

6

YS 51, 1-(beta-naphtylmethyl)-6,7-dihydroxy-1,2,3,4,-tetrahydroisoquinoline, protects endothelial cells against hydrogen peroxide-induced injury via carbon monoxide derived from heme oxygenase-1.

Heo JM, Kim HJ, Ha YM, Park MK, Kang YJ, Lee YS, Seo HG, Lee JH, Yun-Choi HS, Chang KC. Heo JM, et al. Among authors: chang kc. Biochem Pharmacol. 2007 Nov 1;74(9):1361-70. doi: 10.1016/j.bcp.2007.07.023. Epub 2007 Jul 21. Biochem Pharmacol. 2007. PMID: 17719563

7

Inhibition of activation of nuclear factor kappaB is responsible for inhibition of inducible nitric oxide synthase expression by higenamine, an active component of aconite root.

Kang YJ, Lee YS, Lee GW, Lee DH, Ryu JC, Yun-Choi HS, Chang KC. Kang YJ, et al. Among authors: chang kc. J Pharmacol Exp Ther. 1999 Oct;291(1):314-20. J Pharmacol Exp Ther. 1999. PMID: 10490919

8

Cardiovascular effect of a naphthylmethyl substituted tetrahydroisoquinoline, YS 49, in rat and rabbit.

Lee YS, Kim CH, Yun-Choi HS, Chang KC. Lee YS, et al. Among authors: chang kc. Life Sci. 1994;55(21):PL415-20. doi: 10.1016/0024-3205(94)00335-1. Life Sci. 1994. PMID: 7968232

9

Comparison of relaxations evoked by photoactivation of NO-containing compounds and nitrergic nerve stimulation in 5-hydroxytryptamine- and potassium-contracted rat gastric fundus.

Chang KC, Koo EB, Lee GW, Kang YJ, Lee HY. Chang KC, et al. Gen Pharmacol. 1998 Apr;30(4):585-91. doi: 10.1016/s0306-3623(97)00326-1. Gen Pharmacol. 1998. PMID: 9522180

10

Inhibition of lipopolysaccharide-induced inducible nitric oxide (iNOS) mRNA expression and nitric oxide production by higenamine in murine peritoneal macrophages.

Lee HY, Lee JS, Kim EJ, Han JW, Lee HW, Kang YJ, Chang KC. Lee HY, et al. Among authors: chang kc. Arch Pharm Res. 1999 Feb;22(1):55-9. doi: 10.1007/BF02976436. Arch Pharm Res. 1999. PMID: 10071960

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