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Importance of mast cell Prss31/transmembrane tryptase/tryptase-γ in lung function and experimental chronic obstructive pulmonary disease and colitis.
Hansbro PM, Hamilton MJ, Fricker M, Gellatly SL, Jarnicki AG, Zheng D, Frei SM, Wong GW, Hamadi S, Zhou S, Foster PS, Krilis SA, Stevens RL. Hansbro PM, et al. Among authors: krilis sa. J Biol Chem. 2014 Jun 27;289(26):18214-27. doi: 10.1074/jbc.M114.548594. Epub 2014 May 12. J Biol Chem. 2014. PMID: 24821729 Free PMC article.
RasGRP4, a new mast cell-restricted Ras guanine nucleotide-releasing protein with calcium- and diacylglycerol-binding motifs. Identification of defective variants of this signaling protein in asthma, mastocytosis, and mast cell leukemia patients and demonstration of the importance of RasGRP4 in mast cell development and function.
Yang Y, Li L, Wong GW, Krilis SA, Madhusudhan MS, Sali A, Stevens RL. Yang Y, et al. Among authors: krilis sa. J Biol Chem. 2002 Jul 12;277(28):25756-74. doi: 10.1074/jbc.M202575200. Epub 2002 Apr 15. J Biol Chem. 2002. PMID: 11956218 Free article.
Biochemical and functional characterization of human transmembrane tryptase (TMT)/tryptase gamma. TMT is an exocytosed mast cell protease that induces airway hyperresponsiveness in vivo via an interleukin-13/interleukin-4 receptor alpha/signal transducer and activator of transcription (STAT) 6-dependent pathway.
Wong GW, Foster PS, Yasuda S, Qi JC, Mahalingam S, Mellor EA, Katsoulotos G, Li L, Boyce JA, Krilis SA, Stevens RL. Wong GW, et al. Among authors: krilis sa. J Biol Chem. 2002 Nov 1;277(44):41906-15. doi: 10.1074/jbc.M205868200. Epub 2002 Aug 22. J Biol Chem. 2002. PMID: 12194977 Free article.
The Diacylglycerol-dependent translocation of ras guanine nucleotide-releasing protein 4 inside a human mast cell line results in substantial phenotypic changes, including expression of interleukin 13 receptor alpha2.
Katsoulotos GP, Qi M, Qi JC, Tanaka K, Hughes WE, Molloy TJ, Adachi R, Stevens RL, Krilis SA. Katsoulotos GP, et al. Among authors: krilis sa. J Biol Chem. 2008 Jan 18;283(3):1610-1621. doi: 10.1074/jbc.M707042200. Epub 2007 Nov 16. J Biol Chem. 2008. PMID: 18024961 Free article.
157 results