Handel TM - Search Results

1

Identification of residues in the monocyte chemotactic protein-1 that contact the MCP-1 receptor, CCR2.

Hemmerich S, Paavola C, Bloom A, Bhakta S, Freedman R, Grunberger D, Krstenansky J, Lee S, McCarley D, Mulkins M, Wong B, Pease J, Mizoue L, Mirzadegan T, Polsky I, Thompson K, Handel TM, Jarnagin K. Hemmerich S, et al. Among authors: handel tm. Biochemistry. 1999 Oct 5;38(40):13013-25. doi: 10.1021/bi991029m. Biochemistry. 1999. PMID: 10529171

2

Heteronuclear (1H, 13C, 15N) NMR assignments and solution structure of the monocyte chemoattractant protein-1 (MCP-1) dimer.

Handel TM, Domaille PJ. Handel TM, et al. Biochemistry. 1996 May 28;35(21):6569-84. doi: 10.1021/bi9602270. Biochemistry. 1996. PMID: 8639605

3

Monomeric monocyte chemoattractant protein-1 (MCP-1) binds and activates the MCP-1 receptor CCR2B.

Paavola CD, Hemmerich S, Grunberger D, Polsky I, Bloom A, Freedman R, Mulkins M, Bhakta S, McCarley D, Wiesent L, Wong B, Jarnagin K, Handel TM. Paavola CD, et al. Among authors: handel tm. J Biol Chem. 1998 Dec 11;273(50):33157-65. doi: 10.1074/jbc.273.50.33157. J Biol Chem. 1998. PMID: 9837883 Free article.

4

Solution structure and dynamics of the CX3C chemokine domain of fractalkine and its interaction with an N-terminal fragment of CX3CR1.

Mizoue LS, Bazan JF, Johnson EC, Handel TM. Mizoue LS, et al. Among authors: handel tm. Biochemistry. 1999 Feb 2;38(5):1402-14. doi: 10.1021/bi9820614. Biochemistry. 1999. PMID: 9931005

5

Identification of surface residues of the monocyte chemotactic protein 1 that affect signaling through the receptor CCR2.

Jarnagin K, Grunberger D, Mulkins M, Wong B, Hemmerich S, Paavola C, Bloom A, Bhakta S, Diehl F, Freedman R, McCarley D, Polsky I, Ping-Tsou A, Kosaka A, Handel TM. Jarnagin K, et al. Among authors: handel tm. Biochemistry. 1999 Dec 7;38(49):16167-77. doi: 10.1021/bi9912239. Biochemistry. 1999. PMID: 10587439

6

The crystal structure of the chemokine domain of fractalkine shows a novel quaternary arrangement.

Hoover DM, Mizoue LS, Handel TM, Lubkowski J. Hoover DM, et al. Among authors: handel tm. J Biol Chem. 2000 Jul 28;275(30):23187-93. doi: 10.1074/jbc.M002584200. J Biol Chem. 2000. PMID: 10770945 Free article.

7

Chemical synthesis of lymphotactin: a glycosylated chemokine with a C-terminal mucin-like domain.

Marcaurelle LA, Mizoue LS, Wilken J, Oldham L, Kent SB, Handel TM, Bertozzi CR. Marcaurelle LA, et al. Among authors: handel tm. Chemistry. 2001 Mar 2;7(5):1129-32. doi: 10.1002/1521-3765(20010302)7:5<1129::aid-chem1129>3.0.co;2-w. Chemistry. 2001. PMID: 11303872

8

Molecular determinants of receptor binding and signaling by the CX3C chemokine fractalkine.

Mizoue LS, Sullivan SK, King DS, Kledal TN, Schwartz TW, Bacon KB, Handel TM. Mizoue LS, et al. Among authors: handel tm. J Biol Chem. 2001 Sep 7;276(36):33906-14. doi: 10.1074/jbc.M101348200. Epub 2001 Jun 29. J Biol Chem. 2001. PMID: 11432858 Free article.

9

Molecular determinants for CC-chemokine recognition by a poxvirus CC-chemokine inhibitor.

Seet BT, Singh R, Paavola C, Lau EK, Handel TM, McFadden G. Seet BT, et al. Among authors: handel tm. Proc Natl Acad Sci U S A. 2001 Jul 31;98(16):9008-13. doi: 10.1073/pnas.171069398. Epub 2001 Jul 24. Proc Natl Acad Sci U S A. 2001. PMID: 11470923 Free PMC article.

10

Identification of the glycosaminoglycan binding site of the CC chemokine, MCP-1: implications for structure and function in vivo.

Lau EK, Paavola CD, Johnson Z, Gaudry JP, Geretti E, Borlat F, Kungl AJ, Proudfoot AE, Handel TM. Lau EK, et al. Among authors: handel tm. J Biol Chem. 2004 May 21;279(21):22294-305. doi: 10.1074/jbc.M311224200. Epub 2004 Mar 18. J Biol Chem. 2004. PMID: 15033992 Free article.

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