Kahn CR - Search Results

1

[Conditional mutagenesis--second generation knockout mice as models for internal diseases].

Brüning JC, Kahn CR, Krone W, Müller-Wieland D. Brüning JC, et al. Among authors: kahn cr. Med Klin (Munich). 1999 Oct 15;94(10):564-9. doi: 10.1007/BF03044954. Med Klin (Munich). 1999. PMID: 10554515 German.

2

Ribosomal subunit kinase-2 is required for growth factor-stimulated transcription of the c-Fos gene.

Bruning JC, Gillette JA, Zhao Y, Bjorbaeck C, Kotzka J, Knebel B, Avci H, Hanstein B, Lingohr P, Moller DE, Krone W, Kahn CR, Muller-Wieland D. Bruning JC, et al. Among authors: kahn cr. Proc Natl Acad Sci U S A. 2000 Mar 14;97(6):2462-7. doi: 10.1073/pnas.97.6.2462. Proc Natl Acad Sci U S A. 2000. PMID: 10716983 Free PMC article.

3

Role of brain insulin receptor in control of body weight and reproduction.

Brüning JC, Gautam D, Burks DJ, Gillette J, Schubert M, Orban PC, Klein R, Krone W, Müller-Wieland D, Kahn CR. Brüning JC, et al. Among authors: kahn cr. Science. 2000 Sep 22;289(5487):2122-5. doi: 10.1126/science.289.5487.2122. Science. 2000. PMID: 11000114

4

An association between NIDDM and a GAA trinucleotide repeat polymorphism in the X25/frataxin (Friedreich's ataxia) gene.

Ristow M, Giannakidou E, Hebinck J, Busch K, Vorgerd M, Kotzka J, Knebel B, Mueller-Berghaus J, Epplen C, Pfeiffer A, Kahn CR, Doria A, Krone W, Mueller-Wieland D. Ristow M, et al. Among authors: kahn cr. Diabetes. 1998 May;47(5):851-4. doi: 10.2337/diabetes.47.5.851. Diabetes. 1998. PMID: 9588463

5

Pertussis toxin inhibits autophosphorylation and activation of the insulin receptor kinase.

Müller-Wieland D, White MF, Behnke B, Gebhardt A, Neumann S, Krone W, Kahn CR. Müller-Wieland D, et al. Among authors: kahn cr. Biochem Biophys Res Commun. 1991 Dec 31;181(3):1479-85. doi: 10.1016/0006-291x(91)92106-t. Biochem Biophys Res Commun. 1991. PMID: 1722405

6

A muscle-specific insulin receptor knockout exhibits features of the metabolic syndrome of NIDDM without altering glucose tolerance.

Brüning JC, Michael MD, Winnay JN, Hayashi T, Hörsch D, Accili D, Goodyear LJ, Kahn CR. Brüning JC, et al. Among authors: kahn cr. Mol Cell. 1998 Nov;2(5):559-69. doi: 10.1016/s1097-2765(00)80155-0. Mol Cell. 1998. PMID: 9844629 Free article.

7

Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes.

Kulkarni RN, Brüning JC, Winnay JN, Postic C, Magnuson MA, Kahn CR. Kulkarni RN, et al. Among authors: kahn cr. Cell. 1999 Feb 5;96(3):329-39. doi: 10.1016/s0092-8674(00)80546-2. Cell. 1999. PMID: 10025399 Free article.

8

Knockout mice challenge our concepts of glucose homeostasis and the pathogenesis of diabetes mellitus.

Kahn CR, Brüning JC, Michael MD, Kulkarni RN. Kahn CR, et al. J Pediatr Endocrinol Metab. 2000;13 Suppl 6:1377-84. doi: 10.1515/jpem-2000-s611. J Pediatr Endocrinol Metab. 2000. PMID: 11202213 Review.

9

The insulin receptor gene and its expression in insulin-resistant mice.

Ludwig S, Muller-Wieland D, Goldstein BJ, Kahn CR. Ludwig S, et al. Among authors: kahn cr. Endocrinology. 1988 Jul;123(1):594-600. doi: 10.1210/endo-123-1-594. Endocrinology. 1988. PMID: 2838265

10

Tissue-specific insulin resistance in mice with mutations in the insulin receptor, IRS-1, and IRS-2.

Kido Y, Burks DJ, Withers D, Bruning JC, Kahn CR, White MF, Accili D. Kido Y, et al. Among authors: kahn cr. J Clin Invest. 2000 Jan;105(2):199-205. doi: 10.1172/JCI7917. J Clin Invest. 2000. PMID: 10642598 Free PMC article.

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