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A new recurrent and specific cryptic translocation, t(5;14)(q35;q32), is associated with expression of the Hox11L2 gene in T acute lymphoblastic leukemia.
Bernard OA, Busson-LeConiat M, Ballerini P, Mauchauffé M, Della Valle V, Monni R, Nguyen Khac F, Mercher T, Penard-Lacronique V, Pasturaud P, Gressin L, Heilig R, Daniel MT, Lessard M, Berger R. Bernard OA, et al. Among authors: della valle v. Leukemia. 2001 Oct;15(10):1495-504. doi: 10.1038/sj.leu.2402249. Leukemia. 2001. PMID: 11587205
HOX11L2/TLX3 is transcriptionally activated through T-cell regulatory elements downstream of BCL11B as a result of the t(5;14)(q35;q32).
Su XY, Della-Valle V, Andre-Schmutz I, Lemercier C, Radford-Weiss I, Ballerini P, Lessard M, Lafage-Pochitaloff M, Mugneret F, Berger R, Romana SP, Bernard OA, Penard-Lacronique V. Su XY, et al. Among authors: della valle v. Blood. 2006 Dec 15;108(13):4198-201. doi: 10.1182/blood-2006-07-032953. Epub 2006 Aug 22. Blood. 2006. PMID: 16926283 Free article. Clinical Trial.
74 results