Intracellular expression and functional properties of an anti-p21Ras scFv derived from a rat hybridoma containing specific lambda and irrelevant kappa light chains.
Cochet O, Kenigsberg M, Delumeau I, Duchesne M, Schweighoffer F, Tocqué B, Teillaud JL.
Cochet O, et al.
Mol Immunol. 1998 Dec;35(17):1097-110. doi: 10.1016/s0161-5890(98)00105-9.
Mol Immunol. 1998.
PMID: 10395199
This scFv was therefore used as control in experiments where another anti-Ras scFv (Y259 scFv, derived from the neutralizing anti-Ras mAb Y13-259) blocked the Ras pathway in vitro and led to tumor regression in a nude mouse model [Cochet, O., Kenigsberg, M., Delumea …
This scFv was therefore used as control in experiments where another anti-Ras scFv (Y259 scFv, derived from the neutralizing anti-Ras mAb Y1 …