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459 results

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Page 1
Development of orally bioavailable bicyclic pyrazolones as inhibitors of tumor necrosis factor-alpha production.
Clark MP, Laughlin SK, Laufersweiler MJ, Bookland RG, Brugel TA, Golebiowski A, Sabat MP, Townes JA, VanRens JC, Djung JF, Natchus MG, De B, Hsieh LC, Xu SC, Walter RL, Mekel MJ, Heitmeyer SA, Brown KK, Juergens K, Taiwo YO, Janusz MJ. Clark MP, et al. Among authors: de b. J Med Chem. 2004 May 20;47(11):2724-7. doi: 10.1021/jm049968m. J Med Chem. 2004. PMID: 15139749
Discovery of potent, achiral matrix metalloproteinase inhibitors.
Pikul S, McDow Dunham KL, Almstead NG, De B, Natchus MG, Anastasio MV, McPhail SJ, Snider CE, Taiwo YO, Rydel T, Dunaway CM, Gu F, Mieling GE. Pikul S, et al. Among authors: de b. J Med Chem. 1998 Sep 10;41(19):3568-71. doi: 10.1021/jm980253r. J Med Chem. 1998. PMID: 9733482 No abstract available.
Design and synthesis of conformationally-constrained MMP inhibitors.
Natchus MG, Cheng M, Wahl CT, Pikul S, Almstead NG, Bradley RS, Taiwo YO, Mieling GE, Dunaway CM, Snider CE, McIver JM, Barnett BL, McPhail SJ, Anastasio MB, De B. Natchus MG, et al. Among authors: de b. Bioorg Med Chem Lett. 1998 Aug 18;8(16):2077-80. doi: 10.1016/s0960-894x(98)00370-9. Bioorg Med Chem Lett. 1998. PMID: 9873489
The next generation of MMP inhibitors. Design and synthesis.
De B, Natchus MG, Cheng M, Pikul S, Almstead NG, Taiwo YO, Snider CE, Chen L, Barnett B, Gu F, Dowty M. De B, et al. Ann N Y Acad Sci. 1999 Jun 30;878:40-60. doi: 10.1111/j.1749-6632.1999.tb07673.x. Ann N Y Acad Sci. 1999. PMID: 10415719 Review.
Design and synthesis of piperazine-based matrix metalloproteinase inhibitors.
Cheng M, De B, Pikul S, Almstead NG, Natchus MG, Anastasio MV, McPhail SJ, Snider CE, Taiwo YO, Chen L, Dunaway CM, Gu F, Dowty ME, Mieling GE, Janusz MJ, Wang-Weigand S. Cheng M, et al. Among authors: de b. J Med Chem. 2000 Feb 10;43(3):369-80. doi: 10.1021/jm990366q. J Med Chem. 2000. PMID: 10669564
Development of new hydroxamate matrix metalloproteinase inhibitors derived from functionalized 4-aminoprolines.
Natchus MG, Bookland RG, De B, Almstead NG, Pikul S, Janusz MJ, Heitmeyer SA, Hookfin EB, Hsieh LC, Dowty ME, Dietsch CR, Patel VS, Garver SM, Gu F, Pokross ME, Mieling GE, Baker TR, Foltz DJ, Peng SX, Bornes DM, Strojnowski MJ, Taiwo YO. Natchus MG, et al. Among authors: de b. J Med Chem. 2000 Dec 28;43(26):4948-63. doi: 10.1021/jm000246e. J Med Chem. 2000. PMID: 11150165
459 results