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RANK-L and RANK: T cells, bone loss, and mammalian evolution.
Theill LE, Boyle WJ, Penninger JM. Theill LE, et al. Among authors: boyle wj. Annu Rev Immunol. 2002;20:795-823. doi: 10.1146/annurev.immunol.20.100301.064753. Epub 2001 Oct 4. Annu Rev Immunol. 2002. PMID: 11861618 Review.
Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation.
Lacey DL, Timms E, Tan HL, Kelley MJ, Dunstan CR, Burgess T, Elliott R, Colombero A, Elliott G, Scully S, Hsu H, Sullivan J, Hawkins N, Davy E, Capparelli C, Eli A, Qian YX, Kaufman S, Sarosi I, Shalhoub V, Senaldi G, Guo J, Delaney J, Boyle WJ. Lacey DL, et al. Among authors: boyle wj. Cell. 1998 Apr 17;93(2):165-76. doi: 10.1016/s0092-8674(00)81569-x. Cell. 1998. PMID: 9568710 Free article.
Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand.
Hsu H, Lacey DL, Dunstan CR, Solovyev I, Colombero A, Timms E, Tan HL, Elliott G, Kelley MJ, Sarosi I, Wang L, Xia XZ, Elliott R, Chiu L, Black T, Scully S, Capparelli C, Morony S, Shimamoto G, Bass MB, Boyle WJ. Hsu H, et al. Among authors: boyle wj. Proc Natl Acad Sci U S A. 1999 Mar 30;96(7):3540-5. doi: 10.1073/pnas.96.7.3540. Proc Natl Acad Sci U S A. 1999. PMID: 10097072 Free PMC article.
The ligand for osteoprotegerin (OPGL) directly activates mature osteoclasts.
Burgess TL, Qian Y, Kaufman S, Ring BD, Van G, Capparelli C, Kelley M, Hsu H, Boyle WJ, Dunstan CR, Hu S, Lacey DL. Burgess TL, et al. Among authors: boyle wj. J Cell Biol. 1999 May 3;145(3):527-38. doi: 10.1083/jcb.145.3.527. J Cell Biol. 1999. PMID: 10225954 Free PMC article.
RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism.
Li J, Sarosi I, Yan XQ, Morony S, Capparelli C, Tan HL, McCabe S, Elliott R, Scully S, Van G, Kaufman S, Juan SC, Sun Y, Tarpley J, Martin L, Christensen K, McCabe J, Kostenuik P, Hsu H, Fletcher F, Dunstan CR, Lacey DL, Boyle WJ. Li J, et al. Among authors: boyle wj. Proc Natl Acad Sci U S A. 2000 Feb 15;97(4):1566-71. doi: 10.1073/pnas.97.4.1566. Proc Natl Acad Sci U S A. 2000. PMID: 10677500 Free PMC article.
90 results