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In the absence of endogenous mouse apolipoprotein E, apolipoprotein E*2(Arg-158 --> Cys) transgenic mice develop more severe hyperlipoproteinemia than apolipoprotein E*3-Leiden transgenic mice.
van Vlijmen BJ, van Dijk KW, van't Hof HB, van Gorp PJ, van der Zee A, van der Boom H, Breuer ML, Hofker MH, Havekes LM. van Vlijmen BJ, et al. Among authors: hofker mh. J Biol Chem. 1996 Nov 29;271(48):30595-602. doi: 10.1074/jbc.271.48.30595. J Biol Chem. 1996. PMID: 8940032 Free article.
In the absence of the low density lipoprotein receptor, human apolipoprotein C1 overexpression in transgenic mice inhibits the hepatic uptake of very low density lipoproteins via a receptor-associated protein-sensitive pathway.
Jong MC, Dahlmans VE, van Gorp PJ, van Dijk KW, Breuer ML, Hofker MH, Havekes LM. Jong MC, et al. Among authors: hofker mh. J Clin Invest. 1996 Nov 15;98(10):2259-67. doi: 10.1172/JCI119036. J Clin Invest. 1996. PMID: 8941642 Free PMC article.
265 results