Moschel RC - Search Results

1

Inhibition of O(6)-methylguanine-DNA methyltransferase increases azoxymethane-induced colonic tumors in rats.

Wali RK, Skarosi S, Hart J, Zhang Y, Dolan ME, Moschel RC, Nguyen L, Mustafi R, Brasitus TA, Bissonnette M. Wali RK, et al. Among authors: moschel rc. Carcinogenesis. 1999 Dec;20(12):2355-60. doi: 10.1093/carcin/20.12.2355. Carcinogenesis. 1999. PMID: 10590233

2

Pharmacokinetics and metabolism in rats of 2,4-diamino-6-benzyloxy-5- nitrosopyrimidine, an inactivator of O6-alkylguanine-DNA alkyltransferase.

Roy SK, Moschel RC, Dolan ME. Roy SK, et al. Among authors: moschel rc. Drug Metab Dispos. 1996 Nov;24(11):1205-11. Drug Metab Dispos. 1996. PMID: 8937854

3

Comparison of the inactivation of mammalian and bacterial O6-alkylguanine-DNA alkyltransferases by O6-benzylguanine and O6-methylguanine.

Dolan ME, Pegg AE, Dumenco LL, Moschel RC, Gerson SL. Dolan ME, et al. Among authors: moschel rc. Carcinogenesis. 1991 Dec;12(12):2305-9. doi: 10.1093/carcin/12.12.2305. Carcinogenesis. 1991. PMID: 1747932

4

Effect of cell cycle inhibition on Cisplatin-induced cytotoxicity.

Fishel ML, Newell DR, Griffin RJ, Davison R, Wang LZ, Curtin NJ, Zuhowski EG, Kasza K, Egorin MJ, Moschel RC, Dolan ME. Fishel ML, et al. Among authors: moschel rc. J Pharmacol Exp Ther. 2005 Jan;312(1):206-13. doi: 10.1124/jpet.104.073924. Epub 2004 Aug 10. J Pharmacol Exp Ther. 2005. PMID: 15304523

5

Effect of O6-benzylguanine on the sensitivity of human colon tumor xenografts to 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU).

Dolan ME, Pegg AE, Moschel RC, Grindey GB. Dolan ME, et al. Among authors: moschel rc. Biochem Pharmacol. 1993 Jul 20;46(2):285-90. doi: 10.1016/0006-2952(93)90416-t. Biochem Pharmacol. 1993. PMID: 8347150

6

The role of O6-alkylguanine-DNA alkyltransferase in protecting Rat4 cells against the mutagenic effects of O6-substituted guanine residues incorporated in codon 12 of the H-ras gene.

Bishop RE, Dunn LL, Pauly GT, Dolan ME, Moschel RC. Bishop RE, et al. Among authors: moschel rc. Carcinogenesis. 1993 Apr;14(4):593-8. doi: 10.1093/carcin/14.4.593. Carcinogenesis. 1993. PMID: 8472320

7

Effect of O6-benzylguanine on the response to 1,3-bis(2-chloroethyl)-1-nitrosourea in the Dunning R3327G model of prostatic cancer.

Dolan ME, Pegg AE, Biser ND, Moschel RC, English HF. Dolan ME, et al. Among authors: moschel rc. Cancer Chemother Pharmacol. 1993;32(3):221-5. doi: 10.1007/BF00685839. Cancer Chemother Pharmacol. 1993. PMID: 8500228

8

O6-alkylguanine-DNA alkyltransferase inactivation by ester prodrugs of O6-benzylguanine derivatives and their rate of hydrolysis by cellular esterases.

Dolan ME, Roy SK, Garbiras BJ, Helft P, Paras P, Chae MY, Moschel RC, Pegg AE. Dolan ME, et al. Among authors: moschel rc. Biochem Pharmacol. 1998 May 15;55(10):1701-9. doi: 10.1016/s0006-2952(98)00047-1. Biochem Pharmacol. 1998. PMID: 9634007

9

Plasma and cerebrospinal fluid pharmacokinetics of O6-benzylguanine and analogues in nonhuman primates.

Long L, Berg SL, Roy SK, McCully CL, Song-Yoo HW, Moschel RC, Balis FM, Dolan ME. Long L, et al. Among authors: moschel rc. Clin Cancer Res. 2000 Sep;6(9):3662-9. Clin Cancer Res. 2000. PMID: 10999759

10

Inactivation of O6-alkylguanine-DNA alkyltransferase by 8-substituted O6-benzylguanine analogs in mice.

Ewesuedo RB, Wilson LR, Friedman HS, Moschel RC, Dolan ME. Ewesuedo RB, et al. Among authors: moschel rc. Cancer Chemother Pharmacol. 2001;47(1):63-9. doi: 10.1007/s002800000202. Cancer Chemother Pharmacol. 2001. PMID: 11221964

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