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High-dose CD34+ cells are not clinically relevant in reducing cytopenia and blood component consumption following myeloablative therapy and peripheral blood progenitor cell transplantation as compared with standard dose.
Lefrère F, Delarue R, Somme D, Levy V, Damaj G, Tu A, Porcher R, Audat F, Boulat C, Cavazzana-Calvo M, Buzyn A, Belanger C, Maillard N, Hermine O, Varet B. Lefrère F, et al. Transfusion. 2002 Apr;42(4):443-50. doi: 10.1046/j.1525-1438.2002.00060.x. Transfusion. 2002. PMID: 12076291
A specific time course for mobilization of peripheral blood CD34+ cells after plerixafor injection in very poor mobilizer patients: impact on the timing of the apheresis procedure.
Lefrère F, Mauge L, Réa D, Ribeil JA, Dal Cortivo L, Brignier AC, Aoun C, Larghéro J, Cavazzana-Calvo M, Micléa JM. Lefrère F, et al. Transfusion. 2013 Mar;53(3):564-9. doi: 10.1111/j.1537-2995.2012.03744.x. Epub 2012 Jun 21. Transfusion. 2013. PMID: 22725259 Clinical Trial.
The VAD chemotherapy regimen plus a G-CSF dose of 10 microg/kg is as effective and less toxic than high-dose cyclophosphamide plus a G-CSF dose of 5 microg/kg for progenitor cell mobilization: results from a monocentric study of 82 patients.
Lefrère F, Zohar S, Ghez D, Delarue R, Audat F, Suarez F, Hermine O, Damaj G, Maillard N, Ribeil JA, Azagury M, Misbahi R, Jondeau K, Cavazzana-Calvo M, Dal Cortivo L, Varet B. Lefrère F, et al. Bone Marrow Transplant. 2006 Apr;37(8):725-9. doi: 10.1038/sj.bmt.1705308. Bone Marrow Transplant. 2006. PMID: 16518433
121 results