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Absence of the transcription factor CCAAT enhancer binding protein alpha results in loss of myeloid identity in bcr/abl-induced malignancy.
Wagner K, Zhang P, Rosenbauer F, Drescher B, Kobayashi S, Radomska HS, Kutok JL, Gilliland DG, Krauter J, Tenen DG. Wagner K, et al. Among authors: zhang p. Proc Natl Acad Sci U S A. 2006 Apr 18;103(16):6338-43. doi: 10.1073/pnas.0508143103. Epub 2006 Apr 10. Proc Natl Acad Sci U S A. 2006. PMID: 16606850 Free PMC article.
C/EBPbeta is required for 'emergency' granulopoiesis.
Hirai H, Zhang P, Dayaram T, Hetherington CJ, Mizuno S, Imanishi J, Akashi K, Tenen DG. Hirai H, et al. Among authors: zhang p. Nat Immunol. 2006 Jul;7(7):732-9. doi: 10.1038/ni1354. Epub 2006 Jun 4. Nat Immunol. 2006. PMID: 16751774
PU.1 is a major downstream target of AML1 (RUNX1) in adult mouse hematopoiesis.
Huang G, Zhang P, Hirai H, Elf S, Yan X, Chen Z, Koschmieder S, Okuno Y, Dayaram T, Growney JD, Shivdasani RA, Gilliland DG, Speck NA, Nimer SD, Tenen DG. Huang G, et al. Among authors: zhang p. Nat Genet. 2008 Jan;40(1):51-60. doi: 10.1038/ng.2007.7. Epub 2007 Nov 11. Nat Genet. 2008. PMID: 17994017
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