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Page 1
Design of potent and selective human cathepsin K inhibitors that span the active site.
Thompson SK, Halbert SM, Bossard MJ, Tomaszek TA, Levy MA, Zhao B, Smith WW, Abdel-Meguid SS, Janson CA, D'Alessio KJ, McQueney MS, Amegadzie BY, Hanning CR, DesJarlais RL, Briand J, Sarkar SK, Huddleston MJ, Ijames CF, Carr SA, Garnes KT, Shu A, Heys JR, Bradbeer J, Zembryki D, Lee-Rykaczewski L, James IE, Lark MW, Drake FH, Gowen M, Gleason JG, Veber DF. Thompson SK, et al. Among authors: briand j. Proc Natl Acad Sci U S A. 1997 Dec 23;94(26):14249-54. doi: 10.1073/pnas.94.26.14249. Proc Natl Acad Sci U S A. 1997. PMID: 9405598 Free PMC article.
Kinetic mechanism and rate-limiting steps of focal adhesion kinase-1.
Schneck JL, Briand J, Chen S, Lehr R, McDevitt P, Zhao B, Smallwood A, Concha N, Oza K, Kirkpatrick R, Yan K, Villa JP, Meek TD, Thrall SH. Schneck JL, et al. Among authors: briand j. Biochemistry. 2010 Aug 24;49(33):7151-63. doi: 10.1021/bi100824v. Biochemistry. 2010. PMID: 20597513
Conformational mobility in cyclic oligopeptides.
Kopple KD, Bean JW, Bhandary KK, Briand J, D'Ambrosio CA, Peishoff CE. Kopple KD, et al. Among authors: briand j. Biopolymers. 1993 Jul;33(7):1093-9. doi: 10.1002/bip.360330711. Biopolymers. 1993. PMID: 8102073
Discovery of a Novel 2,6-Disubstituted Glucosamine Series of Potent and Selective Hexokinase 2 Inhibitors.
Lin H, Zeng J, Xie R, Schulz MJ, Tedesco R, Qu J, Erhard KF, Mack JF, Raha K, Rendina AR, Szewczuk LM, Kratz PM, Jurewicz AJ, Cecconie T, Martens S, McDevitt PJ, Martin JD, Chen SB, Jiang Y, Nickels L, Schwartz BJ, Smallwood A, Zhao B, Campobasso N, Qian Y, Briand J, Rominger CM, Oleykowski C, Hardwicke MA, Luengo JI. Lin H, et al. Among authors: briand j. ACS Med Chem Lett. 2015 Dec 28;7(3):217-22. doi: 10.1021/acsmedchemlett.5b00214. eCollection 2016 Mar 10. ACS Med Chem Lett. 2015. PMID: 26985301 Free PMC article.
Quinoline 3-sulfonamides inhibit lactate dehydrogenase A and reverse aerobic glycolysis in cancer cells.
Billiard J, Dennison JB, Briand J, Annan RS, Chai D, Colón M, Dodson CS, Gilbert SA, Greshock J, Jing J, Lu H, McSurdy-Freed JE, Orband-Miller LA, Mills GB, Quinn CJ, Schneck JL, Scott GF, Shaw AN, Waitt GM, Wooster RF, Duffy KJ. Billiard J, et al. Among authors: briand j. Cancer Metab. 2013 Sep 6;1(1):19. doi: 10.1186/2049-3002-1-19. Cancer Metab. 2013. PMID: 24280423 Free PMC article.
390 results