Lugnier C - Search Results

1

Anti-inflammatory activities of a new series of selective phosphodiesterase 4 inhibitors derived from 9-benzyladenine.

Boichot E, Wallace JL, Germain N, Corbel M, Lugnier C, Lagente V, Bourguignon JJ. Boichot E, et al. Among authors: lugnier c. J Pharmacol Exp Ther. 2000 Feb;292(2):647-53. J Pharmacol Exp Ther. 2000. PMID: 10640302

2

Anti-TNF-alpha properties of new 9-benzyladenine derivatives with selective phosphodiesterase-4- inhibiting properties.

Reimund JM, Raboisson P, Pinna G, Lugnier C, Bourguignon JJ, Muller CD. Reimund JM, et al. Among authors: lugnier c. Biochem Biophys Res Commun. 2001 Oct 26;288(2):427-34. doi: 10.1006/bbrc.2001.5786. Biochem Biophys Res Commun. 2001. PMID: 11606060

3

Disease progression in MRL/lpr lupus-prone mice is reduced by NCS 613, a specific cyclic nucleotide phosphodiesterase type 4 (PDE4) inhibitor.

Keravis T, Monneaux F, Yougbaré I, Gazi L, Bourguignon JJ, Muller S, Lugnier C. Keravis T, et al. Among authors: lugnier c. PLoS One. 2012;7(1):e28899. doi: 10.1371/journal.pone.0028899. Epub 2012 Jan 11. PLoS One. 2012. PMID: 22247763 Free PMC article.

4

Design, synthesis and structure-activity relationships of a series of 9-substituted adenine derivatives as selective phosphodiesterase type-4 inhibitors.

Raboisson P, Lugnier C, Muller C, Reimund JM, Schultz D, Pinna G, Le Bec A, Basaran H, Desaubry L, Gaudiot F, Seloum M, Bourguignon JJ. Raboisson P, et al. Among authors: lugnier c. Eur J Med Chem. 2003 Feb;38(2):199-214. doi: 10.1016/s0223-5234(02)01446-0. Eur J Med Chem. 2003. PMID: 12620664

5

Cyclic nucleotide phosphodiesterase type 4 inhibitors: evaluation of pyrazolo[1,5-a]-1,3,5-triazine ring system as an adenine bioisostere.

Raboisson P, Schultz D, Muller C, Reimund JM, Pinna G, Mathieu R, Bernard P, Do QT, Desjarlais RL, Justiano H, Lugnier C, Bourguignon JJ. Raboisson P, et al. Among authors: lugnier c. Eur J Med Chem. 2008 Apr;43(4):816-29. doi: 10.1016/j.ejmech.2007.05.016. Epub 2007 Jun 8. Eur J Med Chem. 2008. PMID: 17640774

6

Inhibition of cyclic adenosine-3',5'-monophosphate phosphodiesterase from vascular smooth muscle by rolipram analogues.

Marivet MC, Bourguignon JJ, Lugnier C, Mann A, Stoclet JC, Wermuth CG. Marivet MC, et al. Among authors: lugnier c. J Med Chem. 1989 Jul;32(7):1450-7. doi: 10.1021/jm00127a009. J Med Chem. 1989. PMID: 2544722

7

9-Benzyladenines: potent and selective cAMP phosphodiesterase inhibitors.

Bourguignon JJ, Désaubry L, Raboisson P, Wermuth CG, Lugnier C. Bourguignon JJ, et al. Among authors: lugnier c. J Med Chem. 1997 Jun 6;40(12):1768-70. doi: 10.1021/jm960827x. J Med Chem. 1997. PMID: 9191951 No abstract available.

8

Solid-phase synthesis and evaluation of libraries of substituted 4,5-dihydropyridazinones as vasodilator agents.

Gouault N, Martin-Chouly CA, Lugnier C, Cupif JF, Tonnelier A, Feger F, Lagente V, David M. Gouault N, et al. Among authors: lugnier c. J Pharm Pharmacol. 2004 Aug;56(8):1029-37. doi: 10.1211/0022357043905. J Pharm Pharmacol. 2004. PMID: 15285848

9

Design of small-sized libraries by combinatorial assembly of linkers and functional groups to a given scaffold: application to the structure-based optimization of a phosphodiesterase 4 inhibitor.

Krier M, Araújo-Júnior JX, Schmitt M, Duranton J, Justiano-Basaran H, Lugnier C, Bourguignon JJ, Rognan D. Krier M, et al. Among authors: lugnier c. J Med Chem. 2005 Jun 2;48(11):3816-22. doi: 10.1021/jm050063y. J Med Chem. 2005. PMID: 15916433

10

Design and synthesis of 3-aminophthalazine derivatives and structural analogues as PDE5 inhibitors: anti-allodynic effect against neuropathic pain in a mouse model.

Bollenbach M, Lugnier C, Kremer M, Salvat E, Megat S, Bihel F, Bourguignon JJ, Barrot M, Schmitt M. Bollenbach M, et al. Among authors: lugnier c. Eur J Med Chem. 2019 Sep 1;177:269-290. doi: 10.1016/j.ejmech.2019.05.026. Epub 2019 May 22. Eur J Med Chem. 2019. PMID: 31158744

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