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Mechanism of activation of beta-D-2'-deoxy-2'-fluoro-2'-c-methylcytidine and inhibition of hepatitis C virus NS5B RNA polymerase.
Murakami E, Bao H, Ramesh M, McBrayer TR, Whitaker T, Micolochick Steuer HM, Schinazi RF, Stuyver LJ, Obikhod A, Otto MJ, Furman PA. Murakami E, et al. Among authors: schinazi rf. Antimicrob Agents Chemother. 2007 Feb;51(2):503-9. doi: 10.1128/AAC.00400-06. Epub 2006 Nov 13. Antimicrob Agents Chemother. 2007. PMID: 17101674 Free PMC article.
Synthesis of N3,5'-cyclo-4-(beta-D-ribofuranosyl)-vic-triazolo[4,5-b]pyridin-5-one and its 3'-deoxysugar analogue as potential anti-hepatitis C virus agents.
Wang P, Hollecker L, Pankiewicz KW, Patterson SE, Whitaker T, McBrayer TR, Tharnish PM, Stuyver LJ, Schinazi RF, Otto MJ, Watanabe KA. Wang P, et al. Among authors: schinazi rf. Nucleosides Nucleotides Nucleic Acids. 2005;24(5-7):957-60. doi: 10.1081/ncn-200059314. Nucleosides Nucleotides Nucleic Acids. 2005. PMID: 16248071
615 results