Schwartz TW - Search Results

1

Potency of ligands correlates with affinity measured against agonist and inverse agonists but not against neutral ligand in constitutively active chemokine receptor.

Rosenkilde MM, Schwartz TW. Rosenkilde MM, et al. Among authors: schwartz tw. Mol Pharmacol. 2000 Mar;57(3):602-9. doi: 10.1124/mol.57.3.602. Mol Pharmacol. 2000. PMID: 10692502

2

The species selectivity of chemically distinct tachykinin nonpeptide antagonists is dependent on common divergent residues of the rat and human neurokinin-1 receptors.

Jensen CJ, Gerard NP, Schwartz TW, Gether U. Jensen CJ, et al. Among authors: schwartz tw. Mol Pharmacol. 1994 Feb;45(2):294-9. Mol Pharmacol. 1994. PMID: 7509441

3

Mutations along transmembrane segment II of the NK-1 receptor affect substance P competition with non-peptide antagonists but not substance P binding.

Rosenkilde MM, Cahir M, Gether U, Hjorth SA, Schwartz TW. Rosenkilde MM, et al. Among authors: schwartz tw. J Biol Chem. 1994 Nov 11;269(45):28160-4. J Biol Chem. 1994. PMID: 7525569 Free article.

4

Analysis of selective binding epitopes for the kappa-opioid receptor antagonist nor-binaltorphimine.

Hjorth SA, Thirstrup K, Grandy DK, Schwartz TW. Hjorth SA, et al. Among authors: schwartz tw. Mol Pharmacol. 1995 Jun;47(6):1089-94. Mol Pharmacol. 1995. PMID: 7541509

5

Interaction between the nonpeptide angiotensin antagonist SKF-108,566 and histidine 256 (HisVI:16) of the angiotensin type 1 receptor.

Schambye HT, Hjorth SA, Weinstock J, Schwartz TW. Schambye HT, et al. Among authors: schwartz tw. Mol Pharmacol. 1995 Mar;47(3):425-31. Mol Pharmacol. 1995. PMID: 7700239

6

Evidence for a common molecular mode of action for chemically distinct nonpeptide antagonists at the neurokinin-1 (substance P) receptor.

Gether U, Emonds-Alt X, Brelière JC, Fujii T, Hagiwara D, Pradier L, Garret C, Johansen TE, Schwartz TW. Gether U, et al. Among authors: schwartz tw. Mol Pharmacol. 1994 Mar;45(3):500-8. Mol Pharmacol. 1994. PMID: 8145735

7

Is there a 'lock' for all agonist 'keys' in 7TM receptors?

Schwartz TW, Rosenkilde MM. Schwartz TW, et al. Trends Pharmacol Sci. 1996 Jun;17(6):213-6. doi: 10.1016/0165-6147(96)10017-1. Trends Pharmacol Sci. 1996. PMID: 8763197 Review. No abstract available.

8

Radioligand-dependent discrepancy in agonist affinities enhanced by mutations in the kappa-opioid receptor.

Hjorth SA, Thirstrup K, Schwartz TW. Hjorth SA, et al. Among authors: schwartz tw. Mol Pharmacol. 1996 Oct;50(4):977-84. Mol Pharmacol. 1996. PMID: 8863844

9

Septide and neurokinin A are high-affinity ligands on the NK-1 receptor: evidence from homologous versus heterologous binding analysis.

Hastrup H, Schwartz TW. Hastrup H, et al. Among authors: schwartz tw. FEBS Lett. 1996 Dec 16;399(3):264-6. doi: 10.1016/s0014-5793(96)01337-3. FEBS Lett. 1996. PMID: 8985159 Free article.

10

Potent inhibition of HIV-1 infectivity in macrophages and lymphocytes by a novel CCR5 antagonist.

Simmons G, Clapham PR, Picard L, Offord RE, Rosenkilde MM, Schwartz TW, Buser R, Wells TN, Proudfoot AE. Simmons G, et al. Among authors: schwartz tw. Science. 1997 Apr 11;276(5310):276-9. doi: 10.1126/science.276.5310.276. Science. 1997. PMID: 9092481

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