Frederick CB - Search Results

1

Lessons learned in applying the U.S. EPA proposed cancer guidelines to specific compounds.

Andersen ME, Meek ME, Boorman GA, Brusick DJ, Cohen SM, Dragan YP, Frederick CB, Goodman JI, Hard GC, O'Flaherty EJ, Robinson DE. Andersen ME, et al. Among authors: frederick cb. Toxicol Sci. 2000 Feb;53(2):159-72. doi: 10.1093/toxsci/53.2.159. Toxicol Sci. 2000. PMID: 10696764

2

U.S. Environmental Protection Agency's revised cancer guidelines for carcinogen risk assessment.

Andersen M, Brusick D, Cohen S, Dragan Y, Frederick C, Goodman JI, Hard G, Meek B, O'Flaherty EJ. Andersen M, et al. Toxicol Appl Pharmacol. 1998 Nov;153(1):133-6. doi: 10.1006/taap.1998.8496. Toxicol Appl Pharmacol. 1998. PMID: 9875307 No abstract available.

3

Implementation of EPA Revised Cancer Assessment Guidelines: Incorporation of Mechanistic and Pharmacokinetic Data.

Page NP, Singh DV, Farland W, Goodman JI, Conolly RB, Andersen ME, Clewell HJ, Frederick CB, Yamasaki H, Lucier G. Page NP, et al. Among authors: frederick cb. Fundam Appl Toxicol. 1997 May;37(1):16-36. doi: 10.1006/faat.1997.2305. Fundam Appl Toxicol. 1997. PMID: 9193920

4

Application of a hybrid CFD-PBPK nasal dosimetry model in an inhalation risk assessment: an example with acrylic acid.

Andersen M, Sarangapani R, Gentry R, Clewell H, Covington T, Frederick CB. Andersen M, et al. Among authors: frederick cb. Toxicol Sci. 2000 Oct;57(2):312-25. doi: 10.1093/toxsci/57.2.312. Toxicol Sci. 2000. PMID: 11006361

5

Physiologically based pharmacokinetic (PBPK) models for nasal tissue dosimetry of organic esters: assessing the state-of-knowledge and risk assessment applications with methyl methacrylate and vinyl acetate.

Andersen ME, Green T, Frederick CB, Bogdanffy MS. Andersen ME, et al. Among authors: frederick cb. Regul Toxicol Pharmacol. 2002 Dec;36(3):234-45. doi: 10.1006/rtph.2002.1576. Regul Toxicol Pharmacol. 2002. PMID: 12473408 Review.

6

Applying simulation modeling to problems in toxicology and risk assessment--a short perspective.

Andersen ME, Clewell HJ 3rd, Frederick CB. Andersen ME, et al. Among authors: frederick cb. Toxicol Appl Pharmacol. 1995 Aug;133(2):181-7. doi: 10.1006/taap.1995.1140. Toxicol Appl Pharmacol. 1995. PMID: 7645013 Review.

7

Dosimetric adjustment factors for methyl methacrylate derived from a steady-state analysis of a physiologically based clearance-extraction model.

Andersen ME, Sarangapani R, Frederick CB, Kimbell JS. Andersen ME, et al. Among authors: frederick cb. Inhal Toxicol. 1999 Oct;11(10):899-926. doi: 10.1080/089583799196709. Inhal Toxicol. 1999. PMID: 10509026

8

A physiologically based pharmacokinetic and pharmacodynamic model to describe the oral dosing of rats with ethyl acrylate and its implications for risk assessment.

Frederick CB, Potter DW, Chang-Mateu MI, Andersen ME. Frederick CB, et al. Toxicol Appl Pharmacol. 1992 Jun;114(2):246-60. doi: 10.1016/0041-008x(92)90075-4. Toxicol Appl Pharmacol. 1992. PMID: 1609417

9

Limiting the uncertainty in risk assessment by the development of physiologically based pharmacokinetic and pharmacodynamic models.

Frederick CB. Frederick CB. Toxicol Lett. 1993 May;68(1-2):159-75. doi: 10.1016/0378-4274(93)90128-k. Toxicol Lett. 1993. PMID: 8516762

10

Summary of panel discussion on the 'advantages/limitations/uncertainties in the use of physiologically based pharmacokinetic and pharmacodynamic models in hazard identification and risk assessment of toxic substances'.

Frederick CB. Frederick CB. Toxicol Lett. 1995 Sep;79(1-3):201-6. doi: 10.1016/0378-4274(95)03371-q. Toxicol Lett. 1995. PMID: 7570657 Review.

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