Lipschultz CA - Search Results

1

Structural differences among monoclonal antibodies with distinct fine specificities and kinetic properties.

Lavoie TB, Mohan S, Lipschultz CA, Grivel JC, Li Y, Mainhart CR, Kam-Morgan LN, Drohan WN, Smith-Gill SJ. Lavoie TB, et al. Among authors: lipschultz ca. Mol Immunol. 1999 Dec;36(17):1189-205. doi: 10.1016/s0161-5890(99)00130-3. Mol Immunol. 1999. PMID: 10698321

2

Temperature differentially affects encounter and docking thermodynamics of antibody--antigen association.

Lipschultz CA, Yee A, Mohan S, Li Y, Smith-Gill SJ. Lipschultz CA, et al. J Mol Recognit. 2002 Jan-Feb;15(1):44-52. doi: 10.1002/jmr.559. J Mol Recognit. 2002. PMID: 11870921

3

Light chain somatic mutations change thermodynamics of binding and water coordination in the HyHEL-10 family of antibodies.

Acchione M, Lipschultz CA, DeSantis ME, Shanmuganathan A, Li M, Wlodawer A, Tarasov S, Smith-Gill SJ. Acchione M, et al. Among authors: lipschultz ca. Mol Immunol. 2009 Dec;47(2-3):457-64. doi: 10.1016/j.molimm.2009.08.018. Epub 2009 Sep 24. Mol Immunol. 2009. PMID: 19781789 Free PMC article.

4

Differences in electrostatic properties at antibody-antigen binding sites: implications for specificity and cross-reactivity.

Sinha N, Mohan S, Lipschultz CA, Smith-Gill SJ. Sinha N, et al. Among authors: lipschultz ca. Biophys J. 2002 Dec;83(6):2946-68. doi: 10.1016/S0006-3495(02)75302-2. Biophys J. 2002. PMID: 12496069 Free PMC article.

5

Experimental design for analysis of complex kinetics using surface plasmon resonance.

Lipschultz CA, Li Y, Smith-Gill S. Lipschultz CA, et al. Methods. 2000 Mar;20(3):310-8. doi: 10.1006/meth.1999.0924. Methods. 2000. PMID: 10694453 Review.

6

Mutations of an epitope hot-spot residue alter rate limiting steps of antigen-antibody protein-protein associations.

Li Y, Lipschultz CA, Mohan S, Smith-Gill SJ. Li Y, et al. Among authors: lipschultz ca. Biochemistry. 2001 Feb 20;40(7):2011-22. doi: 10.1021/bi0014148. Biochemistry. 2001. PMID: 11329268

7

Understanding antibody-antigen associations by molecular dynamics simulations: detection of important intra- and inter-molecular salt bridges.

Sinha N, Li Y, Lipschultz CA, Smith-Gill SJ. Sinha N, et al. Among authors: lipschultz ca. Cell Biochem Biophys. 2007;47(3):361-75. doi: 10.1007/s12013-007-0031-8. Cell Biochem Biophys. 2007. PMID: 17652781

8

Association energetics of cross-reactive and specific antibodies.

Mohan S, Kourentzi K, Schick KA, Uehara C, Lipschultz CA, Acchione M, Desantis ME, Smith-Gill SJ, Willson RC. Mohan S, et al. Among authors: lipschultz ca. Biochemistry. 2009 Feb 17;48(6):1390-8. doi: 10.1021/bi801901d. Biochemistry. 2009. PMID: 19166328 Free PMC article.

9

Specific fluorine labeling of the HyHEL10 antibody affects antigen binding and dynamics.

Acchione M, Lee YC, DeSantis ME, Lipschultz CA, Wlodawer A, Li M, Shanmuganathan A, Walter RL, Smith-Gill S, Barchi JJ Jr. Acchione M, et al. Among authors: lipschultz ca. Biochemistry. 2012 Jul 31;51(30):6017-27. doi: 10.1021/bi300455t. Epub 2012 Jul 16. Biochemistry. 2012. PMID: 22769726 Free PMC article.

10

Schweinfurthin A selectively inhibits proliferation and Rho signaling in glioma and neurofibromatosis type 1 tumor cells in a NF1-GRD-dependent manner.

Turbyville TJ, Gürsel DB, Tuskan RG, Walrath JC, Lipschultz CA, Lockett SJ, Wiemer DF, Beutler JA, Reilly KM. Turbyville TJ, et al. Among authors: lipschultz ca. Mol Cancer Ther. 2010 May;9(5):1234-43. doi: 10.1158/1535-7163.MCT-09-0834. Epub 2010 May 4. Mol Cancer Ther. 2010. PMID: 20442305 Free PMC article.

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