Bedard J - Search Results

1

Antiviral properties of a series of 1,6-naphthyridine and 7, 8-dihydroisoquinoline derivatives exhibiting potent activity against human cytomegalovirus.

Bedard J, May S, L'Heureux L, Stamminger T, Copsey A, Drach J, Huffman J, Chan L, Jin H, Rando RF. Bedard J, et al. Antimicrob Agents Chemother. 2000 Apr;44(4):929-37. doi: 10.1128/AAC.44.4.929-937.2000. Antimicrob Agents Chemother. 2000. PMID: 10722493 Free PMC article.

A series of 1,6-naphthyridine (L. Chan, H. Jin, T. Stefanac, J. F. Lavallee, G. Falardeau, W. Wang, J. Bedard, S. May, and L. Yuen, J. Med. Chem. 42:3023-3025, 1999) and isoquinoline (L. Chan, H. Jin, T. Stefanac, W. Wang, J. F. Lavallee, J …

A series of 1,6-naphthyridine (L. Chan, H. Jin, T. Stefanac, J. F. Lavallee, G. Falardeau, W. Wang, J. Bedard, S. May, …

2

Comparative study of the anti-human cytomegalovirus activities and toxicities of a tetrahydrofuran phosphonate analogue of guanosine and cidofovir.

Bedard J, May S, Lis M, Tryphonas L, Drach J, Huffman J, Sidwell R, Chan L, Bowlin T, Rando R. Bedard J, et al. Antimicrob Agents Chemother. 1999 Mar;43(3):557-67. doi: 10.1128/AAC.43.3.557. Antimicrob Agents Chemother. 1999. PMID: 10049267 Free PMC article.

3

A high throughput colorimetric cell proliferation assay for the identification of human cytomegalovirus inhibitors.

Bedard J, May S, Barbeau D, Yuen L, Rando RF, Bowlin TL. Bedard J, et al. Antiviral Res. 1999 Feb;41(1):35-43. doi: 10.1016/s0166-3542(98)00061-8. Antiviral Res. 1999. PMID: 10321577

4

Isoquinoline-6-carboxamides as potent and selective anti-human cytomegalovirus (HCMV) inhibitors.

Chan L, Jin H, Stefanac T, Wang W, Lavallée JF, Bédard J, May S. Chan L, et al. Among authors: bedard j. Bioorg Med Chem Lett. 1999 Sep 6;9(17):2583-6. doi: 10.1016/s0960-894x(99)00435-7. Bioorg Med Chem Lett. 1999. PMID: 10498213

5

Design and evaluation of dihydroisoquinolines as potent and orally bioavailable human cytomegalovirus inhibitors.

Chan L, Stefanac T, Turcotte N, Hu Z, Chen Y, Bédard J, May S, Jin H. Chan L, et al. Among authors: bedard j. Bioorg Med Chem Lett. 2000 Jul 3;10(13):1477-80. doi: 10.1016/s0960-894x(00)00265-1. Bioorg Med Chem Lett. 2000. PMID: 10888336

6

Design and synthesis of new potent human cytomegalovirus (HCMV) inhibitors based on internally hydrogen-bonded 1,6-naphthyridines.

Chan L, Stefanac T, Lavallée JF, Jin H, Bédard J, May S, Falardeau G. Chan L, et al. Among authors: bedard j. Bioorg Med Chem Lett. 2001 Jan 22;11(2):103-5. doi: 10.1016/s0960-894x(00)00607-7. Bioorg Med Chem Lett. 2001. PMID: 11206437

7

Design and synthesis of a potent macrocyclic 1,6-naphthyridine anti-human cytomegalovirus (HCMV) inhibitors.

Falardeau G, Lachance H, St-Pierre A, Yannopoulos CG, Drouin M, Bédard J, Chan L. Falardeau G, et al. Among authors: bedard j. Bioorg Med Chem Lett. 2005 Mar 15;15(6):1693-5. doi: 10.1016/j.bmcl.2005.01.050. Bioorg Med Chem Lett. 2005. PMID: 15745823

8

Identification of novel nucleotide phosphonate analogs with potent anti-HCMV activity.

Nguyen-Ba P, Turcotte N, Yuen L, Bédard J, Quimpère M, Chan L. Nguyen-Ba P, et al. Among authors: bedard j. Bioorg Med Chem Lett. 1998 Dec 15;8(24):3561-6. doi: 10.1016/s0960-894x(98)00649-0. Bioorg Med Chem Lett. 1998. PMID: 9934471

9

Discovery of 1,6-naphthyridines as a novel class of potent and selective human cytomegalovirus inhibitors.

Chan L, Jin H, Stefanac T, Lavallée JF, Falardeau G, Wang W, Bédard J, May S, Yuen L. Chan L, et al. Among authors: bedard j. J Med Chem. 1999 Aug 12;42(16):3023-5. doi: 10.1021/jm9902483. J Med Chem. 1999. PMID: 10447945 No abstract available.

10

Design and SAR study of a novel class of nucleotide analogues as potent anti-HCMV agents.

Nguyen-Ba N, Chan L, Quimpère M, Turcotte N, Lee N, Mitchell H, Bédard J. Nguyen-Ba N, et al. Among authors: bedard j. Nucleosides Nucleotides. 1999 Apr-May;18(4-5):821-7. doi: 10.1080/15257779908041570. Nucleosides Nucleotides. 1999. PMID: 10432685

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