Wengel J - Search Results

1

Structural basis of cleavage by RNase H of hybrids of arabinonucleic acids and RNA.

Minasov G, Teplova M, Nielsen P, Wengel J, Egli M. Minasov G, et al. Among authors: wengel j. Biochemistry. 2000 Apr 4;39(13):3525-32. doi: 10.1021/bi992792j. Biochemistry. 2000. PMID: 10736151

2

The solution structure of a DNA duplex containing a single 1-(2-O,3-C-ethylene-beta-D-arabinofuranosyl)thymidine nucleoside.

Jørgensen LB, Nielsen P, Wengel J, Jacobsen JP. Jørgensen LB, et al. Among authors: wengel j. J Biomol Struct Dyn. 2000 Aug;18(1):45-57. doi: 10.1080/07391102.2000.10506646. J Biomol Struct Dyn. 2000. PMID: 11021651

3

Incorporation of (R)- and (S)-3',4'-seco-thymidine into oligodeoxynucleotides: hybridization properties and enzymatic stability.

Nielsen P, Kirpekar F, Wengel J. Nielsen P, et al. Among authors: wengel j. Nucleic Acids Res. 1994 Mar 11;22(5):703-10. doi: 10.1093/nar/22.5.703. Nucleic Acids Res. 1994. PMID: 8139908 Free PMC article.

4

Synthesis and evaluation of oligodeoxynucleotides containing acyclic nucleosides: introduction of three novel analogues and a summary.

Nielsen P, Dreiøe LH, Wengel J. Nielsen P, et al. Among authors: wengel j. Bioorg Med Chem. 1995 Jan;3(1):19-28. doi: 10.1016/0968-0896(94)00143-q. Bioorg Med Chem. 1995. PMID: 8612043

5

Parallel RNA-strand recognition by 2'-amino-beta-L-LNA.

Kumar TS, Ostergaard ME, Sharma PK, Nielsen P, Wengel J, Hrdlicka PJ. Kumar TS, et al. Among authors: wengel j. Bioorg Med Chem Lett. 2009 May 1;19(9):2396-9. doi: 10.1016/j.bmcl.2009.03.079. Epub 2009 Mar 24. Bioorg Med Chem Lett. 2009. PMID: 19356930

6

Parallel nucleic acid recognition by the LNA (locked nucleic acid) stereoisomers beta-L-LNA and alpha-D-LNA; studies in the mirror image world.

Christensen NK, Bryld T, Sørensen MD, Arar K, Wengel J, Nielsen P. Christensen NK, et al. Among authors: wengel j. Chem Commun (Camb). 2004 Feb 7;(3):282-3. doi: 10.1039/b312321a. Epub 2003 Dec 19. Chem Commun (Camb). 2004. PMID: 14740038

7

NMR solution structure of dsDNA containing a bicyclic D-arabino-configured nucleotide fixed in an O4'-endo sugar conformation.

Tømmerholt HV, Christensen NK, Nielsen P, Wengel J, Stein PC, Jacobsen JP, Petersen M. Tømmerholt HV, et al. Among authors: wengel j. Org Biomol Chem. 2003 May 21;1(10):1790-7. doi: 10.1039/b300848g. Org Biomol Chem. 2003. PMID: 12926371

8

Chemically modified oligonucleotides with efficient RNase H response.

Vester B, Boel AM, Lobedanz S, Babu BR, Raunkjaer M, Lindegaard D, Raunak, Hrdlicka PJ, Højland T, Sharma PK, Kumar S, Nielsen P, Wengel J. Vester B, et al. Among authors: wengel j. Bioorg Med Chem Lett. 2008 Apr 1;18(7):2296-300. doi: 10.1016/j.bmcl.2008.03.004. Epub 2008 Mar 6. Bioorg Med Chem Lett. 2008. PMID: 18356048

9

LNA (locked nucleic acid): high-affinity targeting of complementary RNA and DNA.

Vester B, Wengel J. Vester B, et al. Among authors: wengel j. Biochemistry. 2004 Oct 26;43(42):13233-41. doi: 10.1021/bi0485732. Biochemistry. 2004. PMID: 15491130 Review.

10

The Eight Stereoisomers of LNA (Locked Nucleic Acid): A Remarkable Family of Strong RNA Binding Molecules We acknowledge the Danish Natural Science Research Council, the Danish Technical Research Council, and Exiqon A/S for financial support. Ms Britta M. Dahl is thanked for oligonucleotide synthesis, Dr. Carl E. Olsen for MALDI-MS analysis, and Ms. Karen Jørgensen for recording CD spectra.

Rajwanshi VK, Håkansson AE, Sørensen MD, Pitsch S, Singh SK, Kumar R, Nielsen P, Wengel J. Rajwanshi VK, et al. Among authors: wengel j. Angew Chem Int Ed Engl. 2000 May;39(9):1656-1659. doi: 10.1002/(sici)1521-3773(20000502)39:9<1656::aid-anie1656>3.0.co;2-q. Angew Chem Int Ed Engl. 2000. PMID: 10820467 No abstract available.

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