Milhous WK - Search Results

1

Methyl-substituted dispiro-1,2,4,5-tetraoxanes: correlations of structural studies with antimalarial activity.

McCullough KJ, Wood JK, Bhattacharjee AK, Dong Y, Kyle DE, Milhous WK, Vennerstrom JL. McCullough KJ, et al. Among authors: milhous wk. J Med Chem. 2000 Mar 23;43(6):1246-9. doi: 10.1021/jm990530+. J Med Chem. 2000. PMID: 10737758

2

Dispiro-1,2,4,5-tetraoxanes: a new class of antimalarial peroxides.

Vennerstrom JL, Fu HN, Ellis WY, Ager AL Jr, Wood JK, Andersen SL, Gerena L, Milhous WK. Vennerstrom JL, et al. Among authors: milhous wk. J Med Chem. 1992 Aug 7;35(16):3023-7. doi: 10.1021/jm00094a015. J Med Chem. 1992. PMID: 1501229

3

Synthesis and antimalarial activity of sixteen dispiro-1,2,4, 5-tetraoxanes: alkyl-substituted 7,8,15,16-tetraoxadispiro[5.2.5. 2]hexadecanes.

Vennerstrom JL, Dong Y, Andersen SL, Ager AL Jr, Fu H, Miller RE, Wesche DL, Kyle DE, Gerena L, Walters SM, Wood JK, Edwards G, Holme AD, McLean WG, Milhous WK. Vennerstrom JL, et al. Among authors: milhous wk. J Med Chem. 2000 Jul 13;43(14):2753-8. doi: 10.1021/jm0000766. J Med Chem. 2000. PMID: 10893313

4

Cholic acid derivatives as 1,2,4,5-tetraoxane carriers: structure and antimalarial and antiproliferative activity.

Opsenica D, Pocsfalvi G, Juranic Z, Tinant B, Declercq JP, Kyle DE, Milhous WK, Solaja BA. Opsenica D, et al. Among authors: milhous wk. J Med Chem. 2000 Aug 24;43(17):3274-82. doi: 10.1021/jm000952f. J Med Chem. 2000. PMID: 10966746

5

Design, synthesis, and evaluation of new chemosensitizers in multi-drug-resistant Plasmodium falciparum.

Guan J, Kyle DE, Gerena L, Zhang Q, Milhous WK, Lin AJ. Guan J, et al. Among authors: milhous wk. J Med Chem. 2002 Jun 20;45(13):2741-8. doi: 10.1021/jm010549o. J Med Chem. 2002. PMID: 12061877

6

Antimalarial and antiproliferative evaluation of bis-steroidal tetraoxanes.

Opsenica D, Angelovski G, Pocsfalvi G, Juranić Z, Zizak Z, Kyle D, Milhous WK, Solaja BA. Opsenica D, et al. Among authors: milhous wk. Bioorg Med Chem. 2003 Jul 3;11(13):2761-8. doi: 10.1016/s0968-0896(03)00224-4. Bioorg Med Chem. 2003. PMID: 12788350

7

Structure-activity relationship study of antimalarial indolo [2,1-b]quinazoline-6,12-diones (tryptanthrins). Three dimensional pharmacophore modeling and identification of new antimalarial candidates.

Bhattacharjee AK, Hartell MG, Nichols DA, Hicks RP, Stanton B, van Hamont JE, Milhous WK. Bhattacharjee AK, et al. Among authors: milhous wk. Eur J Med Chem. 2004 Jan;39(1):59-67. doi: 10.1016/j.ejmech.2003.10.004. Eur J Med Chem. 2004. PMID: 14987834

8

Bisquinolines. 1. N,N-bis(7-chloroquinolin-4-yl)alkanediamines with potential against chloroquine-resistant malaria.

Vennerstrom JL, Ellis WY, Ager AL Jr, Andersen SL, Gerena L, Milhous WK. Vennerstrom JL, et al. Among authors: milhous wk. J Med Chem. 1992 May 29;35(11):2129-34. doi: 10.1021/jm00089a025. J Med Chem. 1992. PMID: 1597862

9

Bisquinolines. 2. Antimalarial N,N-bis(7-chloroquinolin-4-yl)heteroalkanediamines.

Vennerstrom JL, Ager AL Jr, Dorn A, Andersen SL, Gerena L, Ridley RG, Milhous WK. Vennerstrom JL, et al. Among authors: milhous wk. J Med Chem. 1998 Oct 22;41(22):4360-4. doi: 10.1021/jm9803828. J Med Chem. 1998. PMID: 9784111

10

Unambiguous synthesis and prophylactic antimalarial activities of imidazolidinedione derivatives.

Zhang Q, Guan J, Sacci J, Ager A, Ellis W, Milhous W, Kyle D, Lin AJ. Zhang Q, et al. J Med Chem. 2005 Oct 6;48(20):6472-81. doi: 10.1021/jm0504252. J Med Chem. 2005. PMID: 16190773

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