Bicknell D - Search Results

1

APC mutations in sporadic colorectal tumors: A mutational "hotspot" and interdependence of the "two hits".

Rowan AJ, Lamlum H, Ilyas M, Wheeler J, Straub J, Papadopoulou A, Bicknell D, Bodmer WF, Tomlinson IP. Rowan AJ, et al. Among authors: bicknell d. Proc Natl Acad Sci U S A. 2000 Mar 28;97(7):3352-7. doi: 10.1073/pnas.97.7.3352. Proc Natl Acad Sci U S A. 2000. PMID: 10737795 Free PMC article.

2

Beta 2-microglobulin gene mutations: a study of established colorectal cell lines and fresh tumors.

Bicknell DC, Rowan A, Bodmer WF. Bicknell DC, et al. Proc Natl Acad Sci U S A. 1994 May 24;91(11):4751-5. doi: 10.1073/pnas.91.11.4751. Proc Natl Acad Sci U S A. 1994. PMID: 8197130 Free PMC article.

3

Tissue typing the HLA-A locus from genomic DNA by sequence-specific PCR: comparison of HLA genotype and surface expression on colorectal tumor cell lines.

Browning MJ, Krausa P, Rowan A, Bicknell DC, Bodmer JG, Bodmer WF. Browning MJ, et al. Among authors: bicknell dc. Proc Natl Acad Sci U S A. 1993 Apr 1;90(7):2842-5. doi: 10.1073/pnas.90.7.2842. Proc Natl Acad Sci U S A. 1993. PMID: 8464898 Free PMC article.

4

SMAD4 mutations in colorectal cancer probably occur before chromosomal instability, but after divergence of the microsatellite instability pathway.

Woodford-Richens KL, Rowan AJ, Gorman P, Halford S, Bicknell DC, Wasan HS, Roylance RR, Bodmer WF, Tomlinson IP. Woodford-Richens KL, et al. Among authors: bicknell dc. Proc Natl Acad Sci U S A. 2001 Aug 14;98(17):9719-23. doi: 10.1073/pnas.171321498. Epub 2001 Jul 31. Proc Natl Acad Sci U S A. 2001. PMID: 11481457 Free PMC article.

5

Loss of CDX1 expression in colorectal carcinoma: promoter methylation, mutation, and loss of heterozygosity analyses of 37 cell lines.

Wong NA, Britton MP, Choi GS, Stanton TK, Bicknell DC, Wilding JL, Bodmer WF. Wong NA, et al. Among authors: bicknell dc. Proc Natl Acad Sci U S A. 2004 Jan 13;101(2):574-9. doi: 10.1073/pnas.0307190101. Epub 2004 Jan 2. Proc Natl Acad Sci U S A. 2004. PMID: 14704280 Free PMC article.

6

Insulin-like growth factor 1 regulates the location, stability, and transcriptional activity of beta-catenin.

Playford MP, Bicknell D, Bodmer WF, Macaulay VM. Playford MP, et al. Among authors: bicknell d. Proc Natl Acad Sci U S A. 2000 Oct 24;97(22):12103-8. doi: 10.1073/pnas.210394297. Proc Natl Acad Sci U S A. 2000. PMID: 11035789 Free PMC article.

7

CDX2 mutations do not account for juvenile polyposis or Peutz-Jeghers syndrome and occur infrequently in sporadic colorectal cancers.

Woodford-Richens KL, Halford S, Rowan A, Bevan S, Aaltonen LA, Wasan H, Bicknell D, Bodmer WF, Houlston RS, Tomlinson IP. Woodford-Richens KL, et al. Among authors: bicknell d. Br J Cancer. 2001 May 18;84(10):1314-6. doi: 10.1054/bjoc.2001.1800. Br J Cancer. 2001. PMID: 11355940 Free PMC article.

8

Combined array-comparative genomic hybridization and single-nucleotide polymorphism-loss of heterozygosity analysis reveals complex changes and multiple forms of chromosomal instability in colorectal cancers.

Gaasenbeek M, Howarth K, Rowan AJ, Gorman PA, Jones A, Chaplin T, Liu Y, Bicknell D, Davison EJ, Fiegler H, Carter NP, Roylance RR, Tomlinson IP. Gaasenbeek M, et al. Among authors: bicknell d. Cancer Res. 2006 Apr 1;66(7):3471-9. doi: 10.1158/0008-5472.CAN-05-3285. Cancer Res. 2006. PMID: 16585170

9

Gastrointestinal differentiation marker Cytokeratin 20 is regulated by homeobox gene CDX1.

Chan CW, Wong NA, Liu Y, Bicknell D, Turley H, Hollins L, Miller CJ, Wilding JL, Bodmer WF. Chan CW, et al. Among authors: bicknell d. Proc Natl Acad Sci U S A. 2009 Feb 10;106(6):1936-41. doi: 10.1073/pnas.0812904106. Epub 2009 Feb 2. Proc Natl Acad Sci U S A. 2009. PMID: 19188603 Free PMC article.

10

Multiple rare variants in different genes account for multifactorial inherited susceptibility to colorectal adenomas.

Fearnhead NS, Wilding JL, Winney B, Tonks S, Bartlett S, Bicknell DC, Tomlinson IP, Mortensen NJ, Bodmer WF. Fearnhead NS, et al. Proc Natl Acad Sci U S A. 2004 Nov 9;101(45):15992-7. doi: 10.1073/pnas.0407187101. Epub 2004 Nov 1. Proc Natl Acad Sci U S A. 2004. PMID: 15520370 Free PMC article.

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