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Binding of stromal derived factor-1alpha (SDF-1alpha) to CXCR4 chemokine receptor in normal human megakaryoblasts but not in platelets induces phosphorylation of mitogen-activated protein kinase p42/44 (MAPK), ELK-1 transcription factor and serine/threonine kinase AKT.
Majka M, Ratajczak J, Kowalska MA, Ratajczak MZ. Majka M, et al. Among authors: kowalska ma. Eur J Haematol. 2000 Mar;64(3):164-72. doi: 10.1034/j.1600-0609.2000.90112.x. Eur J Haematol. 2000. PMID: 10997882
Numerous growth factors, cytokines, and chemokines are secreted by human CD34(+) cells, myeloblasts, erythroblasts, and megakaryoblasts and regulate normal hematopoiesis in an autocrine/paracrine manner.
Majka M, Janowska-Wieczorek A, Ratajczak J, Ehrenman K, Pietrzkowski Z, Kowalska MA, Gewirtz AM, Emerson SG, Ratajczak MZ. Majka M, et al. Among authors: kowalska ma. Blood. 2001 May 15;97(10):3075-85. doi: 10.1182/blood.v97.10.3075. Blood. 2001. PMID: 11342433 Free article.
Chemokines and thrombogenicity.
Lambert MP, Sachais BS, Kowalska MA. Lambert MP, et al. Among authors: kowalska ma. Thromb Haemost. 2007 May;97(5):722-9. doi: 10.1160/th07-01-0046. Thromb Haemost. 2007. PMID: 17479182 Review.
108 results