Pio B - Search Results

1

Nonsteroidal progesterone receptor antagonists based on 6-thiophenehydroquinolines.

Zhi L, Tegley CM, Pio B, West SJ, Marschke KB, Mais DE, Jones TK. Zhi L, et al. Among authors: pio b. Bioorg Med Chem Lett. 2000 Mar 6;10(5):415-8. doi: 10.1016/s0960-894x(00)00011-1. Bioorg Med Chem Lett. 2000. PMID: 10743938

2

Synthesis and biological activity of 5-methylidene 1,2-dihydrochromeno[3,4-f]quinoline derivatives as progesterone receptor modulators.

Zhi L, Tegley CM, Pio B, Edwards JP, Jones TK, Marschke KB, Mais DE, Risek B, Schrader WT. Zhi L, et al. Among authors: pio b. Bioorg Med Chem Lett. 2003 Jun 16;13(12):2071-4. doi: 10.1016/s0960-894x(03)00255-5. Bioorg Med Chem Lett. 2003. PMID: 12781197

3

Development of progesterone receptor antagonists from 1,2-dihydrochromeno[3,4-f]quinoline agonist pharmacophore.

Zhi L, Ringgenberg JD, Edwards JP, Tegley CM, West SJ, Pio B, Motamedi M, Jones TK, Marschke KB, Mais DE, Schrader WT. Zhi L, et al. Among authors: pio b. Bioorg Med Chem Lett. 2003 Jun 16;13(12):2075-8. doi: 10.1016/s0960-894x(03)00256-7. Bioorg Med Chem Lett. 2003. PMID: 12781198

4

5-benzylidene-1,2-dihydrochromeno[3,4-f]quinolines as selective progesterone receptor modulators.

Zhi L, Tegley CM, Pio B, Edwards JP, Motamedi M, Jones TK, Marschke KB, Mais DE, Risek B, Schrader WT. Zhi L, et al. Among authors: pio b. J Med Chem. 2003 Sep 11;46(19):4104-12. doi: 10.1021/jm020477g. J Med Chem. 2003. PMID: 12954062

5

Preparation and biological evaluation of indole, benzimidazole, and thienopyrrole piperazine carboxamides: potent human histamine h(4) antagonists.

Venable JD, Cai H, Chai W, Dvorak CA, Grice CA, Jablonowski JA, Shah CR, Kwok AK, Ly KS, Pio B, Wei J, Desai PJ, Jiang W, Nguyen S, Ling P, Wilson SJ, Dunford PJ, Thurmond RL, Lovenberg TW, Karlsson L, Carruthers NI, Edwards JP. Venable JD, et al. Among authors: pio b. J Med Chem. 2005 Dec 29;48(26):8289-98. doi: 10.1021/jm0502081. J Med Chem. 2005. PMID: 16366610

6

Discovery of an androgen receptor modulator pharmacophore based on 2-quinolinones.

van Oeveren A, Pio BA, Tegley CM, Higuchi RI, Wu M, Jones TK, Marschke KB, Negro-Vilar A, Zhi L. van Oeveren A, et al. Among authors: pio ba. Bioorg Med Chem Lett. 2007 Mar 15;17(6):1523-6. doi: 10.1016/j.bmcl.2007.01.007. Epub 2007 Jan 13. Bioorg Med Chem Lett. 2007. PMID: 17257838

7

Pyrazole-based cathepsin S inhibitors with improved cellular potency.

Wei J, Pio BA, Cai H, Meduna SP, Sun S, Gu Y, Jiang W, Thurmond RL, Karlsson L, Edwards JP. Wei J, et al. Bioorg Med Chem Lett. 2007 Oct 15;17(20):5525-8. doi: 10.1016/j.bmcl.2007.08.038. Epub 2007 Aug 22. Bioorg Med Chem Lett. 2007. PMID: 17822900

8

RXR-LXR heterodimer modulators for the potential treatment of dyslipidemia.

Lagu B, Pio B, Lebedev R, Yang M, Pelton PD. Lagu B, et al. Among authors: pio b. Bioorg Med Chem Lett. 2007 Jun 15;17(12):3497-503. doi: 10.1016/j.bmcl.2007.01.047. Epub 2007 Jan 24. Bioorg Med Chem Lett. 2007. PMID: 17485209

9

Dihydro-[1H]-quinolin-2-ones as retinoid X receptor (RXR) agonists for potential treatment of dyslipidemia.

Lagu B, Lebedev R, Pio B, Yang M, Pelton PD. Lagu B, et al. Among authors: pio b. Bioorg Med Chem Lett. 2007 Jun 15;17(12):3491-6. doi: 10.1016/j.bmcl.2007.01.049. Epub 2007 Jan 25. Bioorg Med Chem Lett. 2007. PMID: 17490875

10

The design and synthesis of novel spirocyclic heterocyclic sulfone ROMK inhibitors as diuretics.

Chobanian HR, Guo Y, Pio B, Tang H, Teumelsan N, Clements M, Frie J, Ferguson R, Guo Z, Thomas-Fowlkes BS, Felix JP, Liu J, Kohler M, Priest B, Hampton C, Pai LY, Corona A, Metzger J, Tong V, Joshi EM, Xu L, Owens K, Maloney K, Sullivan K, Pasternak A. Chobanian HR, et al. Among authors: pio b. Bioorg Med Chem Lett. 2017 Feb 15;27(4):1109-1114. doi: 10.1016/j.bmcl.2016.10.032. Epub 2016 Oct 13. Bioorg Med Chem Lett. 2017. PMID: 28111141

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