Hynes NE - Search Results

1

ErbB2 potentiates breast tumor proliferation through modulation of p27(Kip1)-Cdk2 complex formation: receptor overexpression does not determine growth dependency.

Lane HA, Beuvink I, Motoyama AB, Daly JM, Neve RM, Hynes NE. Lane HA, et al. Among authors: hynes ne. Mol Cell Biol. 2000 May;20(9):3210-23. doi: 10.1128/MCB.20.9.3210-3223.2000. Mol Cell Biol. 2000. PMID: 10757805 Free PMC article.

2

The efficacy of ErbB receptor-targeted anticancer therapeutics is influenced by the availability of epidermal growth factor-related peptides.

Motoyama AB, Hynes NE, Lane HA. Motoyama AB, et al. Among authors: hynes ne. Cancer Res. 2002 Jun 1;62(11):3151-8. Cancer Res. 2002. PMID: 12036928

3

NDF/heregulin-induced cell cycle changes and apoptosis in breast tumour cells: role of PI3 kinase and p38 MAP kinase pathways.

Daly JM, Olayioye MA, Wong AM, Neve R, Lane HA, Maurer FG, Hynes NE. Daly JM, et al. Among authors: hynes ne. Oncogene. 1999 Jun 10;18(23):3440-51. doi: 10.1038/sj.onc.1202700. Oncogene. 1999. PMID: 10376522

4

Effects of oncogenic ErbB2 on G1 cell cycle regulators in breast tumour cells.

Neve RM, Sutterlüty H, Pullen N, Lane HA, Daly JM, Krek W, Hynes NE. Neve RM, et al. Among authors: hynes ne. Oncogene. 2000 Mar 23;19(13):1647-56. doi: 10.1038/sj.onc.1203470. Oncogene. 2000. PMID: 10763821

5

Myc and mammary cancer: Myc is a downstream effector of the ErbB2 receptor tyrosine kinase.

Hynes NE, Lane HA. Hynes NE, et al. J Mammary Gland Biol Neoplasia. 2001 Jan;6(1):141-50. doi: 10.1023/a:1009528918064. J Mammary Gland Biol Neoplasia. 2001. PMID: 11467449 Review.

6

Modulation of p27/Cdk2 complex formation through 4D5-mediated inhibition of HER2 receptor signaling.

Lane HA, Motoyama AB, Beuvink I, Hynes NE. Lane HA, et al. Among authors: hynes ne. Ann Oncol. 2001;12 Suppl 1:S21-2. doi: 10.1093/annonc/12.suppl_1.s21. Ann Oncol. 2001. PMID: 11521716 Free article. Review.

7

The role of overexpressed HER2 in transformation.

Neve RM, Lane HA, Hynes NE. Neve RM, et al. Among authors: hynes ne. Ann Oncol. 2001;12 Suppl 1:S9-13. doi: 10.1093/annonc/12.suppl_1.s9. Ann Oncol. 2001. PMID: 11521729 Free article. Review.

8

BAD: a good therapeutic target?

Motoyama AB, Hynes NE. Motoyama AB, et al. Among authors: hynes ne. Breast Cancer Res. 2003;5(1):27-30. doi: 10.1186/bcr552. Epub 2002 Oct 18. Breast Cancer Res. 2003. PMID: 12559042 Free PMC article.

9

ERBB receptors and cancer: the complexity of targeted inhibitors.

Hynes NE, Lane HA. Hynes NE, et al. Nat Rev Cancer. 2005 May;5(5):341-54. doi: 10.1038/nrc1609. Nat Rev Cancer. 2005. PMID: 15864276 Review.

10

ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling.

Graus-Porta D, Beerli RR, Daly JM, Hynes NE. Graus-Porta D, et al. Among authors: hynes ne. EMBO J. 1997 Apr 1;16(7):1647-55. doi: 10.1093/emboj/16.7.1647. EMBO J. 1997. PMID: 9130710 Free PMC article.

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