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A novel cationic lipid greatly enhances plasmid DNA delivery and expression in mouse lung.
Wheeler CJ, Felgner PL, Tsai YJ, Marshall J, Sukhu L, Doh SG, Hartikka J, Nietupski J, Manthorpe M, Nichols M, Plewe M, Liang X, Norman J, Smith A, Cheng SH. Wheeler CJ, et al. Proc Natl Acad Sci U S A. 1996 Oct 15;93(21):11454-9. doi: 10.1073/pnas.93.21.11454. Proc Natl Acad Sci U S A. 1996. PMID: 8876156 Free PMC article.
Preexisting immunity and low expression in primates highlight translational challenges for liver-directed AAV8-mediated gene therapy.
Hurlbut GD, Ziegler RJ, Nietupski JB, Foley JW, Woodworth LA, Meyers E, Bercury SD, Pande NN, Souza DW, Bree MP, Lukason MJ, Marshall J, Cheng SH, Scheule RK. Hurlbut GD, et al. Among authors: nietupski jb. Mol Ther. 2010 Nov;18(11):1983-94. doi: 10.1038/mt.2010.175. Epub 2010 Aug 24. Mol Ther. 2010. PMID: 20736932 Free PMC article.
Restoration of cyclic adenosine monophosphate-stimulated chloride channel activity in human cystic fibrosis tracheobronchial submucosal gland cells by adenovirus-mediated and cationic lipid-mediated gene transfer.
Jiang C, Finkbeiner WE, Widdicombe JH, Fang SL, Wang KX, Nietupski JB, Hehir KM, Cheng SH. Jiang C, et al. Among authors: nietupski jb. Am J Respir Cell Mol Biol. 1999 Jun;20(6):1107-15. doi: 10.1165/ajrcmb.20.6.3440. Am J Respir Cell Mol Biol. 1999. PMID: 10340929
20 results