Smith RG - Search Results

1

Ligand-induced stabilization of PPARgamma monitored by NMR spectroscopy: implications for nuclear receptor activation.

Johnson BA, Wilson EM, Li Y, Moller DE, Smith RG, Zhou G. Johnson BA, et al. Among authors: smith rg. J Mol Biol. 2000 Apr 28;298(2):187-94. doi: 10.1006/jmbi.2000.3636. J Mol Biol. 2000. PMID: 10764590

2

Nuclear receptors have distinct affinities for coactivators: characterization by fluorescence resonance energy transfer.

Zhou G, Cummings R, Li Y, Mitra S, Wilkinson HA, Elbrecht A, Hermes JD, Schaeffer JM, Smith RG, Moller DE. Zhou G, et al. Among authors: smith rg. Mol Endocrinol. 1998 Oct;12(10):1594-604. doi: 10.1210/mend.12.10.0176. Mol Endocrinol. 1998. PMID: 9773982

3

Novel peroxisome proliferator-activated receptor (PPAR) gamma and PPARdelta ligands produce distinct biological effects.

Berger J, Leibowitz MD, Doebber TW, Elbrecht A, Zhang B, Zhou G, Biswas C, Cullinan CA, Hayes NS, Li Y, Tanen M, Ventre J, Wu MS, Berger GD, Mosley R, Marquis R, Santini C, Sahoo SP, Tolman RL, Smith RG, Moller DE. Berger J, et al. Among authors: smith rg. J Biol Chem. 1999 Mar 5;274(10):6718-25. doi: 10.1074/jbc.274.10.6718. J Biol Chem. 1999. PMID: 10037770 Free article.

4

L-764406 is a partial agonist of human peroxisome proliferator-activated receptor gamma. The role of Cys313 in ligand binding.

Elbrecht A, Chen Y, Adams A, Berger J, Griffin P, Klatt T, Zhang B, Menke J, Zhou G, Smith RG, Moller DE. Elbrecht A, et al. Among authors: smith rg. J Biol Chem. 1999 Mar 19;274(12):7913-22. doi: 10.1074/jbc.274.12.7913. J Biol Chem. 1999. PMID: 10075686 Free article.

5

Activation of PPARdelta alters lipid metabolism in db/db mice.

Leibowitz MD, Fiévet C, Hennuyer N, Peinado-Onsurbe J, Duez H, Bergera J, Cullinan CA, Sparrow CP, Baffic J, Berger GD, Santini C, Marquis RW, Tolman RL, Smith RG, Moller DE, Auwerx J. Leibowitz MD, et al. Among authors: smith rg. FEBS Lett. 2000 May 19;473(3):333-6. doi: 10.1016/s0014-5793(00)01554-4. FEBS Lett. 2000. PMID: 10818235 Free article.

6

Sex hormone-binding globulin mediates prostate androgen receptor action via a novel signaling pathway.

Ding VD, Moller DE, Feeney WP, Didolkar V, Nakhla AM, Rhodes L, Rosner W, Smith RG. Ding VD, et al. Among authors: smith rg. Endocrinology. 1998 Jan;139(1):213-8. doi: 10.1210/endo.139.1.5681. Endocrinology. 1998. PMID: 9421417

7

Discovery of a small molecule insulin mimetic with antidiabetic activity in mice.

Zhang B, Salituro G, Szalkowski D, Li Z, Zhang Y, Royo I, Vilella D, Díez MT, Pelaez F, Ruby C, Kendall RL, Mao X, Griffin P, Calaycay J, Zierath JR, Heck JV, Smith RG, Moller DE. Zhang B, et al. Among authors: smith rg. Science. 1999 May 7;284(5416):974-7. doi: 10.1126/science.284.5416.974. Science. 1999. PMID: 10320380

8

Ligand activation domain of human orphan growth hormone (GH) secretagogue receptor (GHS-R) conserved from Pufferfish to humans.

Palyha OC, Feighner SD, Tan CP, McKee KK, Hreniuk DL, Gao YD, Schleim KD, Yang L, Morriello GJ, Nargund R, Patchett AA, Howard AD, Smith RG. Palyha OC, et al. Among authors: smith rg. Mol Endocrinol. 2000 Jan;14(1):160-9. doi: 10.1210/mend.14.1.0412. Mol Endocrinol. 2000. PMID: 10628755

9

Thiazolidinediones produce a conformational change in peroxisomal proliferator-activated receptor-gamma: binding and activation correlate with antidiabetic actions in db/db mice.

Berger J, Bailey P, Biswas C, Cullinan CA, Doebber TW, Hayes NS, Saperstein R, Smith RG, Leibowitz MD. Berger J, et al. Among authors: smith rg. Endocrinology. 1996 Oct;137(10):4189-95. doi: 10.1210/endo.137.10.8828476. Endocrinology. 1996. PMID: 8828476

10

Identification of Phe313 of the gonadotropin-releasing hormone (GnRH) receptor as a site critical for the binding of nonpeptide GnRH antagonists.

Cui J, Smith RG, Mount GR, Lo JL, Yu J, Walsh TF, Singh SB, DeVita RJ, Goulet MT, Schaeffer JM, Cheng K. Cui J, et al. Among authors: smith rg. Mol Endocrinol. 2000 May;14(5):671-81. doi: 10.1210/mend.14.5.0464. Mol Endocrinol. 2000. PMID: 10809231

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