Wittrup KD - Search Results

1

In vitro evolution of a T cell receptor with high affinity for peptide/MHC.

Holler PD, Holman PO, Shusta EV, O'Herrin S, Wittrup KD, Kranz DM. Holler PD, et al. Among authors: wittrup kd. Proc Natl Acad Sci U S A. 2000 May 9;97(10):5387-92. doi: 10.1073/pnas.080078297. Proc Natl Acad Sci U S A. 2000. PMID: 10779548 Free PMC article.

2

Isolation of anti-T cell receptor scFv mutants by yeast surface display.

Kieke MC, Cho BK, Boder ET, Kranz DM, Wittrup KD. Kieke MC, et al. Among authors: wittrup kd. Protein Eng. 1997 Nov;10(11):1303-10. doi: 10.1093/protein/10.11.1303. Protein Eng. 1997. PMID: 9514119

3

Increasing the secretory capacity of Saccharomyces cerevisiae for production of single-chain antibody fragments.

Shusta EV, Raines RT, Plückthun A, Wittrup KD. Shusta EV, et al. Among authors: wittrup kd. Nat Biotechnol. 1998 Aug;16(8):773-7. doi: 10.1038/nbt0898-773. Nat Biotechnol. 1998. PMID: 9702778

4

A yeast surface display system for the discovery of ligands that trigger cell activation.

Cho BK, Kieke MC, Boder ET, Wittrup KD, Kranz DM. Cho BK, et al. Among authors: wittrup kd. J Immunol Methods. 1998 Nov 1;220(1-2):179-88. doi: 10.1016/s0022-1759(98)00158-6. J Immunol Methods. 1998. PMID: 9839939

5

Biosynthetic polypeptide libraries.

Shusta EV, VanAntwerp J, Wittrup KD. Shusta EV, et al. Among authors: wittrup kd. Curr Opin Biotechnol. 1999 Apr;10(2):117-22. doi: 10.1016/s0958-1669(99)80020-2. Curr Opin Biotechnol. 1999. PMID: 10209135 Review.

6

Selection of functional T cell receptor mutants from a yeast surface-display library.

Kieke MC, Shusta EV, Boder ET, Teyton L, Wittrup KD, Kranz DM. Kieke MC, et al. Among authors: wittrup kd. Proc Natl Acad Sci U S A. 1999 May 11;96(10):5651-6. doi: 10.1073/pnas.96.10.5651. Proc Natl Acad Sci U S A. 1999. PMID: 10318939 Free PMC article.

7

Yeast polypeptide fusion surface display levels predict thermal stability and soluble secretion efficiency.

Shusta EV, Kieke MC, Parke E, Kranz DM, Wittrup KD. Shusta EV, et al. Among authors: wittrup kd. J Mol Biol. 1999 Oct 8;292(5):949-56. doi: 10.1006/jmbi.1999.3130. J Mol Biol. 1999. PMID: 10512694

8

Directed evolution of a stable scaffold for T-cell receptor engineering.

Shusta EV, Holler PD, Kieke MC, Kranz DM, Wittrup KD. Shusta EV, et al. Among authors: wittrup kd. Nat Biotechnol. 2000 Jul;18(7):754-9. doi: 10.1038/77325. Nat Biotechnol. 2000. PMID: 10888844

9

Directed evolution of antibody fragments with monovalent femtomolar antigen-binding affinity.

Boder ET, Midelfort KS, Wittrup KD. Boder ET, et al. Among authors: wittrup kd. Proc Natl Acad Sci U S A. 2000 Sep 26;97(20):10701-5. doi: 10.1073/pnas.170297297. Proc Natl Acad Sci U S A. 2000. PMID: 10984501 Free PMC article.

10

High affinity T cell receptors from yeast display libraries block T cell activation by superantigens.

Kieke MC, Sundberg E, Shusta EV, Mariuzza RA, Wittrup KD, Kranz DM. Kieke MC, et al. Among authors: wittrup kd. J Mol Biol. 2001 Apr 13;307(5):1305-15. doi: 10.1006/jmbi.2001.4560. J Mol Biol. 2001. PMID: 11292343

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