Vernier JM - Search Results

1

Analgesic profile of the nicotinic acetylcholine receptor agonists, (+)-epibatidine and ABT-594 in models of persistent inflammatory and neuropathic pain.

Kesingland AC, Gentry CT, Panesar MS, Bowes MA, Vernier JM, Cube R, Walker K, Urban L. Kesingland AC, et al. Among authors: vernier jm. Pain. 2000 May;86(1-2):113-8. doi: 10.1016/s0304-3959(00)00233-5. Pain. 2000. PMID: 10779668

2

Allosteric potentiators of the metabotropic glutamate receptor 2 (mGlu2). Part 2: 4-thiopyridyl acetophenones as non-tetrazole containing mGlu2 receptor potentiators.

Pinkerton AB, Cube RV, Hutchinson JH, James JK, Gardner MF, Schaffhauser H, Rowe BA, Daggett LP, Vernier JM. Pinkerton AB, et al. Among authors: vernier jm. Bioorg Med Chem Lett. 2004 Dec 6;14(23):5867-72. doi: 10.1016/j.bmcl.2004.09.028. Bioorg Med Chem Lett. 2004. PMID: 15501058

3

Allosteric potentiators of the metabotropic glutamate receptor 2 (mGlu2). Part 3: Identification and biological activity of indanone containing mGlu2 receptor potentiators.

Pinkerton AB, Cube RV, Hutchinson JH, James JK, Gardner MF, Rowe BA, Schaffhauser H, Rodriguez DE, Campbell UC, Daggett LP, Vernier JM. Pinkerton AB, et al. Among authors: vernier jm. Bioorg Med Chem Lett. 2005 Mar 15;15(6):1565-71. doi: 10.1016/j.bmcl.2005.01.077. Bioorg Med Chem Lett. 2005. PMID: 15745798

4

3-(2-Ethoxy-4-{4-[3-hydroxy-2-methyl-4-(3-methylbutanoyl)phenoxy]butoxy}phenyl)propanoic acid: a brain penetrant allosteric potentiator at the metabotropic glutamate receptor 2 (mGluR2).

Cube RV, Vernier JM, Hutchinson JH, Gardner MF, James JK, Rowe BA, Schaffhauser H, Daggett L, Pinkerton AB. Cube RV, et al. Among authors: vernier jm. Bioorg Med Chem Lett. 2005 May 2;15(9):2389-93. doi: 10.1016/j.bmcl.2005.02.078. Bioorg Med Chem Lett. 2005. PMID: 15837331

5

Allosteric potentiators of the metabotropic glutamate receptor 2 (mGlu2). Part 1: Identification and synthesis of phenyl-tetrazolyl acetophenones.

Pinkerton AB, Cube RV, Hutchinson JH, Rowe BA, Schaffhauser H, Zhao X, Daggett LP, Vernier JM. Pinkerton AB, et al. Among authors: vernier jm. Bioorg Med Chem Lett. 2004 Nov 1;14(21):5329-32. doi: 10.1016/j.bmcl.2004.08.020. Bioorg Med Chem Lett. 2004. PMID: 15454221

6

The potential of subtype-selective neuronal nicotinic acetylcholine receptor agonists as therapeutic agents.

Lloyd GK, Menzaghi F, Bontempi B, Suto C, Siegel R, Akong M, Stauderman K, Velicelebi G, Johnson E, Harpold MM, Rao TS, Sacaan AI, Chavez-Noriega LE, Washburn MS, Vernier JM, Cosford ND, McDonald LA. Lloyd GK, et al. Among authors: vernier jm. Life Sci. 1998;62(17-18):1601-6. doi: 10.1016/s0024-3205(98)00114-3. Life Sci. 1998. PMID: 9585143 Review.

7

Diaryl substituted pyrazoles as potent CCR2 receptor antagonists.

Pinkerton AB, Huang D, Cube RV, Hutchinson JH, Struthers M, Ayala JM, Vicario PP, Patel SR, Wisniewski T, DeMartino JA, Vernier JM. Pinkerton AB, et al. Among authors: vernier jm. Bioorg Med Chem Lett. 2007 Feb 1;17(3):807-13. doi: 10.1016/j.bmcl.2006.10.060. Epub 2006 Oct 25. Bioorg Med Chem Lett. 2007. PMID: 17088058

8

In vivo pharmacological characterization of (+/-)-4-[2-(1-methyl-2-pyrrolidinyl)ethyl]thiophenol hydrochloride (SIB-1553A), a novel cholinergic ligand: microdialysis studies.

Rao TS, Reid RT, Correa LD, Santori EM, Gardner MF, Sacaan AI, Lorrain D, Vernier JM. Rao TS, et al. Among authors: vernier jm. Brain Res. 2003 Oct 3;986(1-2):71-81. doi: 10.1016/s0006-8993(03)03174-3. Brain Res. 2003. PMID: 12965231

9

Pharmacological characterization and identification of amino acids involved in the positive modulation of metabotropic glutamate receptor subtype 2.

Schaffhauser H, Rowe BA, Morales S, Chavez-Noriega LE, Yin R, Jachec C, Rao SP, Bain G, Pinkerton AB, Vernier JM, Bristow LJ, Varney MA, Daggett LP. Schaffhauser H, et al. Among authors: vernier jm. Mol Pharmacol. 2003 Oct;64(4):798-810. doi: 10.1124/mol.64.4.798. Mol Pharmacol. 2003. PMID: 14500736

10

Phenyl-tetrazolyl acetophenones: discovery of positive allosteric potentiatiors for the metabotropic glutamate 2 receptor.

Pinkerton AB, Vernier JM, Schaffhauser H, Rowe BA, Campbell UC, Rodriguez DE, Lorrain DS, Baccei CS, Daggett LP, Bristow LJ. Pinkerton AB, et al. Among authors: vernier jm. J Med Chem. 2004 Aug 26;47(18):4595-9. doi: 10.1021/jm040088h. J Med Chem. 2004. PMID: 15317469

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