Goudgaon NM - Search Results

1

Modulation of plasma uridine concentration by 5-(phenylselenenyl)acyclouridine, an inhibitor of uridine phosphorylase: relevance to chemotherapy.

Ashour OM, Al Safarjalani ON, Naguib FN, Goudgaon NM, Schinazi RF, el Kouni MH. Ashour OM, et al. Among authors: goudgaon nm. Cancer Chemother Pharmacol. 2000;45(5):351-61. doi: 10.1007/s002800051002. Cancer Chemother Pharmacol. 2000. PMID: 10803917

2

Effects of modifications in the pentose moiety and conformational changes on the binding of nucleoside ligands to uridine phosphorylase from Toxoplasma gondii.

el Kouni MH, Naguib FN, Panzica RP, Otter BA, Chu SH, Gosselin G, Chu CK, Schinazi RF, Shealy YF, Goudgaon N, Ozerov AA, Ueda T, Iltzsch MH. el Kouni MH, et al. Biochem Pharmacol. 1996 Jun 28;51(12):1687-700. doi: 10.1016/0006-2952(96)00213-4. Biochem Pharmacol. 1996. PMID: 8687484

3

Effect of administration of 5-(phenylselenenyl)acyclouridine, an inhibitor of uridine phosphorylase, on the anti-tumor efficacy of 5-fluoro-2'-deoxyuridine against murine colon tumor C26-10.

Ashour OM, Naguib FN, Goudgaon NM, Schinazi RF, el Kouni MH. Ashour OM, et al. Among authors: goudgaon nm. Biochem Pharmacol. 2000 Sep 1;60(5):687-92. doi: 10.1016/s0006-2952(00)00375-0. Biochem Pharmacol. 2000. PMID: 10927027

4

5-phenylthioacyclouridine: a potent and specific inhibitor of uridine phosphorylase.

el Kouni MH, Goudgaon NM, Rafeeq M, Al Safarjalani ON, Schinazi RF, Naguib FN. el Kouni MH, et al. Among authors: goudgaon nm. Biochem Pharmacol. 2000 Sep 15;60(6):851-6. doi: 10.1016/s0006-2952(00)00410-x. Biochem Pharmacol. 2000. PMID: 10930540

5

Effect of 5-(phenylselenenyl)acyclouridine, an inhibitor of uridine phosphorylase, on plasma concentration of uridine released from 2',3',5'-tri-O-acetyluridine, a prodrug of uridine: relevance to uridine rescue in chemotherapy.

Ashour OM, Naguib FN, Goudgaon NM, Schinazi RF, el Kouni MH. Ashour OM, et al. Among authors: goudgaon nm. Cancer Chemother Pharmacol. 2000;46(3):235-40. doi: 10.1007/s002800000138. Cancer Chemother Pharmacol. 2000. PMID: 11021741

6

Modulation of the pharmacokinetics of endogenous plasma uridine by 5-(phenylthio)acyclouridine, a uridine phosphorylase inhibitor: implications for chemotherapy.

Al Safarjalani ON, Zhou XJ, Naguib FN, Goudgaon NM, Schinazi RF, el Kouni MH. Al Safarjalani ON, et al. Among authors: goudgaon nm. Cancer Chemother Pharmacol. 2001 Aug;48(2):145-50. doi: 10.1007/s002800100292. Cancer Chemother Pharmacol. 2001. PMID: 11565561

7

Resistance of human immunodeficiency virus type 1 to acyclic 6-phenylselenenyl- and 6-phenylthiopyrimidines.

Nguyen MH, Schinazi RF, Shi C, Goudgaon NM, McKenna PM, Mellors JW. Nguyen MH, et al. Among authors: goudgaon nm. Antimicrob Agents Chemother. 1994 Oct;38(10):2409-14. doi: 10.1128/AAC.38.10.2409. Antimicrob Agents Chemother. 1994. PMID: 7840579 Free PMC article.

8

Phenylselenenyl- and phenylthio-substituted pyrimidines as inhibitors of dihydrouracil dehydrogenase and uridine phosphorylase.

Goudgaon NM, Naguib FN, el Kouni MH, Schinazi RF. Goudgaon NM, et al. J Med Chem. 1993 Dec 24;36(26):4250-4. doi: 10.1021/jm00078a015. J Med Chem. 1993. PMID: 8277507

9

Catabolic disposition of 3'-azido-2',3'-dideoxyuridine in hepatocytes with evidence of azido reduction being a general catabolic pathway of 3'-azido-2',3'-dideoxynucleosides.

Cretton EM, Xie MY, Goudgaon NM, Schinazi RF, Chu CK, Sommadossi JP. Cretton EM, et al. Among authors: goudgaon nm. Biochem Pharmacol. 1992 Sep 1;44(5):973-80. doi: 10.1016/0006-2952(92)90130-b. Biochem Pharmacol. 1992. PMID: 1326966

10

Catabolism of 3'-azido-3'-deoxythymidine in hepatocytes and liver microsomes, with evidence of formation of 3'-amino-3'-deoxythymidine, a highly toxic catabolite for human bone marrow cells.

Cretton EM, Xie MY, Bevan RJ, Goudgaon NM, Schinazi RF, Sommadossi JP. Cretton EM, et al. Among authors: goudgaon nm. Mol Pharmacol. 1991 Feb;39(2):258-66. Mol Pharmacol. 1991. PMID: 1996084

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