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The TEL/platelet-derived growth factor beta receptor (PDGF beta R) fusion in chronic myelomonocytic leukemia is a transforming protein that self-associates and activates PDGF beta R kinase-dependent signaling pathways.
Carroll M, Tomasson MH, Barker GF, Golub TR, Gilliland DG. Carroll M, et al. Among authors: gilliland dg. Proc Natl Acad Sci U S A. 1996 Dec 10;93(25):14845-50. doi: 10.1073/pnas.93.25.14845. Proc Natl Acad Sci U S A. 1996. PMID: 8962143 Free PMC article.
The TEL gene and human leukemia.
Golub TR, McLean T, Stegmaier K, Carroll M, Tomasson M, Gilliland DG. Golub TR, et al. Among authors: gilliland dg. Biochim Biophys Acta. 1996 Aug 8;1288(1):M7-10. doi: 10.1016/0304-419x(96)00015-7. Biochim Biophys Acta. 1996. PMID: 8764840 Review. No abstract available.
Activating alleles of JAK3 in acute megakaryoblastic leukemia.
Walters DK, Mercher T, Gu TL, O'Hare T, Tyner JW, Loriaux M, Goss VL, Lee KA, Eide CA, Wong MJ, Stoffregen EP, McGreevey L, Nardone J, Moore SA, Crispino J, Boggon TJ, Heinrich MC, Deininger MW, Polakiewicz RD, Gilliland DG, Druker BJ. Walters DK, et al. Among authors: gilliland dg. Cancer Cell. 2006 Jul;10(1):65-75. doi: 10.1016/j.ccr.2006.06.002. Cancer Cell. 2006. PMID: 16843266 Free article.
A murine model of CML blast crisis induced by cooperation between BCR/ABL and NUP98/HOXA9.
Dash AB, Williams IR, Kutok JL, Tomasson MH, Anastasiadou E, Lindahl K, Li S, Van Etten RA, Borrow J, Housman D, Druker B, Gilliland DG. Dash AB, et al. Among authors: gilliland dg. Proc Natl Acad Sci U S A. 2002 May 28;99(11):7622-7. doi: 10.1073/pnas.102583199. Proc Natl Acad Sci U S A. 2002. PMID: 12032333 Free PMC article.
The JAK2V617F activating mutation occurs in chronic myelomonocytic leukemia and acute myeloid leukemia, but not in acute lymphoblastic leukemia or chronic lymphocytic leukemia.
Levine RL, Loriaux M, Huntly BJ, Loh ML, Beran M, Stoffregen E, Berger R, Clark JJ, Willis SG, Nguyen KT, Flores NJ, Estey E, Gattermann N, Armstrong S, Look AT, Griffin JD, Bernard OA, Heinrich MC, Gilliland DG, Druker B, Deininger MW. Levine RL, et al. Among authors: gilliland dg. Blood. 2005 Nov 15;106(10):3377-9. doi: 10.1182/blood-2005-05-1898. Epub 2005 Aug 4. Blood. 2005. PMID: 16081687 Free PMC article. Clinical Trial.
275 results