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Failure to unwind causes cancer. Genome stability.
Watt PM, Hickson ID. Watt PM, et al. Among authors: hickson id. Curr Biol. 1996 Mar 1;6(3):265-7. doi: 10.1016/s0960-9822(02)00474-8. Curr Biol. 1996. PMID: 8805238 Free article. Review.
The Bloom's syndrome gene product is a 3'-5' DNA helicase.
Karow JK, Chakraverty RK, Hickson ID. Karow JK, et al. Among authors: hickson id. J Biol Chem. 1997 Dec 5;272(49):30611-4. doi: 10.1074/jbc.272.49.30611. J Biol Chem. 1997. PMID: 9388193 Free article.
The Bloom's syndrome helicase unwinds G4 DNA.
Sun H, Karow JK, Hickson ID, Maizels N. Sun H, et al. Among authors: hickson id. J Biol Chem. 1998 Oct 16;273(42):27587-92. doi: 10.1074/jbc.273.42.27587. J Biol Chem. 1998. PMID: 9765292 Free article.
Attenuation of drug-stimulated topoisomerase II-DNA cleavable complex formation in wild-type HL-60 cells treated with an intracellular calcium buffer is correlated with decreased cytotoxicity and site-specific hypophosphorylation of topoisomerase IIalpha.
Aoyama M, Grabowski DR, Dubyak GR, Constantinou AI, Rybicki LA, Bukowski RM, Ganapathi MK, Hickson ID, Ganapathi R. Aoyama M, et al. Among authors: hickson id. Biochem J. 1998 Dec 15;336 ( Pt 3)(Pt 3):727-33. doi: 10.1042/bj3360727. Biochem J. 1998. PMID: 9841887 Free PMC article.
Oligomeric ring structure of the Bloom's syndrome helicase.
Karow JK, Newman RH, Freemont PS, Hickson ID. Karow JK, et al. Among authors: hickson id. Curr Biol. 1999 Jun 3;9(11):597-600. doi: 10.1016/s0960-9822(99)80264-4. Curr Biol. 1999. PMID: 10359700 Free article.
315 results