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Sulfhydryls of tubulin. A probe to detect conformational changes of tubulin.
Roychowdhury M, Sarkar N, Manna T, Bhattacharyya S, Sarkar T, Basusarkar P, Roy S, Bhattacharyya B. Roychowdhury M, et al. Among authors: sarkar t, sarkar n. Eur J Biochem. 2000 Jun;267(12):3469-76. doi: 10.1046/j.1432-1327.2000.01369.x. Eur J Biochem. 2000. PMID: 10848962 Free article.
MAP2 prevents protein aggregation and facilitates reactivation of unfolded enzymes.
Sarkar T, Mitra G, Gupta S, Manna T, Poddar A, Panda D, Das KP, Bhattacharyya B. Sarkar T, et al. Eur J Biochem. 2004 Apr;271(8):1488-96. doi: 10.1111/j.1432-1033.2004.04053.x. Eur J Biochem. 2004. PMID: 15066174 Free article.
In vitro studies from our laboratory showed that dimeric tubulin can prevent stress induced aggregation of substrate proteins, can resist thermal deactivation of enzymes and can also refold enzymes from their fully denatured state [Manna, T., Sarkar, T., Podd …
In vitro studies from our laboratory showed that dimeric tubulin can prevent stress induced aggregation of substrate proteins, can resist th …
Inhibition of tubulin polymerization by select alkenyldiarylmethanes.
Cullen MD, Sarkar T, Hamel E, Hartman TL, Watson KM, Buckheit RW Jr, Pannecouque C, De Clercq E, Cushman M. Cullen MD, et al. Among authors: sarkar t. Bioorg Med Chem Lett. 2008 Jan 15;18(2):469-73. doi: 10.1016/j.bmcl.2007.11.114. Epub 2007 Dec 4. Bioorg Med Chem Lett. 2008. PMID: 18083556 Free PMC article.
Synthesis and biological evaluation of 2-(3',4',5'-trimethoxybenzoyl)-3-N,N-dimethylamino benzo[b]furan derivatives as inhibitors of tubulin polymerization.
Romagnoli R, Baraldi PG, Sarkar T, Carrion MD, Cruz-Lopez O, Lopez Cara C, Tolomeo M, Grimaudo S, Di Cristina A, Pipitone MR, Balzarini J, Gambari R, Ilaria L, Saletti R, Brancale A, Hamel E. Romagnoli R, et al. Among authors: sarkar t. Bioorg Med Chem. 2008 Sep 15;16(18):8419-26. doi: 10.1016/j.bmc.2008.08.029. Epub 2008 Aug 17. Bioorg Med Chem. 2008. PMID: 18755591 Free PMC article.
New arylthioindoles and related bioisosteres at the sulfur bridging group. 4. Synthesis, tubulin polymerization, cell growth inhibition, and molecular modeling studies.
La Regina G, Sarkar T, Bai R, Edler MC, Saletti R, Coluccia A, Piscitelli F, Minelli L, Gatti V, Mazzoccoli C, Palermo V, Mazzoni C, Falcone C, Scovassi AI, Giansanti V, Campiglia P, Porta A, Maresca B, Hamel E, Brancale A, Novellino E, Silvestri R. La Regina G, et al. Among authors: sarkar t. J Med Chem. 2009 Dec 10;52(23):7512-27. doi: 10.1021/jm900016t. J Med Chem. 2009. PMID: 19601594 Free PMC article.
649 results