Simms P - Search Results

1

HAI-1 is an independent predictor of lung cancer mortality and is required for M1 macrophage polarization.

Borowicz S, Principe DR, Dorman MJ, McHenry AJ, Sondarva G, Kumar S, Ananthanarayanan V, Simms PE, Hess A, Rana A. Borowicz S, et al. Among authors: simms pe. PLoS One. 2021 Jun 29;16(6):e0252197. doi: 10.1371/journal.pone.0252197. eCollection 2021. PLoS One. 2021. PMID: 34185790 Free PMC article.

2

CXCR7 Reactivates ERK Signaling to Promote Resistance to EGFR Kinase Inhibitors in NSCLC.

Becker JH, Gao Y, Soucheray M, Pulido I, Kikuchi E, Rodríguez ML, Gandhi R, Lafuente-Sanchis A, Aupí M, Alcácer Fernández-Coronado J, Martín-Martorell P, Cremades A, Galbis-Caravajal JM, Alcácer J, Christensen CL, Simms P, Hess A, Asahina H, Kahle MP, Al-Shahrour F, Borgia JA, Lahoz A, Insa A, Juan O, Jänne PA, Wong KK, Carretero J, Shimamura T. Becker JH, et al. Among authors: simms p. Cancer Res. 2019 Sep 1;79(17):4439-4452. doi: 10.1158/0008-5472.CAN-19-0024. Epub 2019 Jul 4. Cancer Res. 2019. PMID: 31273063 Free PMC article.

3

Inhibition of HER2 Increases JAGGED1-dependent Breast Cancer Stem Cells: Role for Membrane JAGGED1.

Shah D, Wyatt D, Baker AT, Simms P, Peiffer DS, Fernandez M, Rakha E, Green A, Filipovic A, Miele L, Osipo C. Shah D, et al. Among authors: simms p. Clin Cancer Res. 2018 Sep 15;24(18):4566-4578. doi: 10.1158/1078-0432.CCR-17-1952. Epub 2018 Jun 12. Clin Cancer Res. 2018. PMID: 29895705 Free PMC article.

4

Altered Peptide Ligands Impact the Diversity of Polyfunctional Phenotypes in T Cell Receptor Gene-Modified T Cells.

Spear TT, Wang Y, Smith TW Jr, Simms PE, Garrett-Mayer E, Hellman LM, Baker BM, Nishimura MI. Spear TT, et al. Among authors: simms pe. Mol Ther. 2018 Apr 4;26(4):996-1007. doi: 10.1016/j.ymthe.2018.01.015. Epub 2018 Feb 2. Mol Ther. 2018. PMID: 29503203 Free PMC article.

5

Circulating exosomes carrying an immunosuppressive cargo interfere with cellular immunotherapy in acute myeloid leukemia.

Hong CS, Sharma P, Yerneni SS, Simms P, Jackson EK, Whiteside TL, Boyiadzis M. Hong CS, et al. Among authors: simms p. Sci Rep. 2017 Oct 31;7(1):14684. doi: 10.1038/s41598-017-14661-w. Sci Rep. 2017. PMID: 29089618 Free PMC article. Clinical Trial.

6

Human tumor-derived exosomes (TEX) regulate Treg functions via cell surface signaling rather than uptake mechanisms.

Muller L, Simms P, Hong CS, Nishimura MI, Jackson EK, Watkins SC, Whiteside TL. Muller L, et al. Among authors: simms p. Oncoimmunology. 2017 Jul 19;6(8):e1261243. doi: 10.1080/2162402X.2016.1261243. eCollection 2017. Oncoimmunology. 2017. PMID: 28919985 Free PMC article.

7

Critical biological parameters modulate affinity as a determinant of function in T-cell receptor gene-modified T-cells.

Spear TT, Wang Y, Foley KC, Murray DC, Scurti GM, Simms PE, Garrett-Mayer E, Hellman LM, Baker BM, Nishimura MI. Spear TT, et al. Among authors: simms pe. Cancer Immunol Immunother. 2017 Nov;66(11):1411-1424. doi: 10.1007/s00262-017-2032-9. Epub 2017 Jun 20. Cancer Immunol Immunother. 2017. PMID: 28634816 Free PMC article.

8

Comparative exploration of multidimensional flow cytometry software: a model approach evaluating T cell polyfunctional behavior.

Spear TT, Nishimura MI, Simms PE. Spear TT, et al. Among authors: simms pe. J Leukoc Biol. 2017 Aug;102(2):551-561. doi: 10.1189/jlb.6A0417-140R. Epub 2017 May 26. J Leukoc Biol. 2017. PMID: 28550117 Free PMC article.

9

Blocking TCR restimulation induced necroptosis in adoptively transferred T cells improves tumor control.

Kesarwani P, Chakraborty P, Gudi R, Chatterjee S, Scurti G, Toth K, Simms P, Husain M, Armeson K, Husain S, Garrett-Mayer E, Vasu C, Nishimura MI, Mehrotra S. Kesarwani P, et al. Among authors: simms p. Oncotarget. 2016 Oct 25;7(43):69371-69383. doi: 10.18632/oncotarget.12674. Oncotarget. 2016. PMID: 27750220 Free PMC article.

10

Efficacy of Adoptive T-cell Therapy Is Improved by Treatment with the Antioxidant N-Acetyl Cysteine, Which Limits Activation-Induced T-cell Death.

Scheffel MJ, Scurti G, Simms P, Garrett-Mayer E, Mehrotra S, Nishimura MI, Voelkel-Johnson C. Scheffel MJ, et al. Among authors: simms p. Cancer Res. 2016 Oct 15;76(20):6006-6016. doi: 10.1158/0008-5472.CAN-16-0587. Cancer Res. 2016. PMID: 27742673 Free PMC article.

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