Arion D - Search Results

1

Synthesis and biophysical properties of arabinonucleic acids (ANA): circular dichroic spectra, melting temperatures, and ribonuclease H susceptibility of ANA.RNA hybrid duplexes.

Noronha AM, Wilds CJ, Lok CN, Viazovkina K, Arion D, Parniak MA, Damha MJ. Noronha AM, et al. Among authors: arion d. Biochemistry. 2000 Jun 20;39(24):7050-62. doi: 10.1021/bi000280v. Biochemistry. 2000. PMID: 10852702

2

Inhibitory potency of R-region specific antisense oligonucleotides against in vitro DNA polymerization and template-switching reactions catalysed by HIV-1 reverse transcriptase.

Borkow G, Arion D, Noronha A, Scartozzi M, Damha MJ, Parniak MA. Borkow G, et al. Among authors: arion d. Int J Biochem Cell Biol. 1997 Nov;29(11):1285-95. doi: 10.1016/s1357-2725(97)00067-8. Int J Biochem Cell Biol. 1997. PMID: 9451826

3

Physicochemical and biochemical properties of 2',5'-linked RNA and 2',5'-RNA:3',5'-RNA "hybrid" duplexes.

Wasner M, Arion D, Borkow G, Noronha A, Uddin AH, Parniak MA, Damha MJ. Wasner M, et al. Among authors: arion d. Biochemistry. 1998 May 19;37(20):7478-86. doi: 10.1021/bi980160b. Biochemistry. 1998. PMID: 9585561

4

Synergistic inhibition of HIV-1 reverse transcriptase DNA polymerase activity and virus replication in vitro by combinations of carboxanilide nonnucleoside compounds.

Fletcher RS, Arion D, Borkow G, Wainberg MA, Dmitrienko GI, Parniak MA. Fletcher RS, et al. Among authors: arion d. Biochemistry. 1995 Aug 15;34(32):10106-12. doi: 10.1021/bi00032a002. Biochemistry. 1995. PMID: 7543775

5

Inhibition of the ribonuclease H and DNA polymerase activities of HIV-1 reverse transcriptase by N-(4-tert-butylbenzoyl)-2-hydroxy-1-naphthaldehyde hydrazone.

Borkow G, Fletcher RS, Barnard J, Arion D, Motakis D, Dmitrienko GI, Parniak MA. Borkow G, et al. Among authors: arion d. Biochemistry. 1997 Mar 18;36(11):3179-85. doi: 10.1021/bi9624696. Biochemistry. 1997. PMID: 9115994

6

Phenotypic mechanism of HIV-1 resistance to 3'-azido-3'-deoxythymidine (AZT): increased polymerization processivity and enhanced sensitivity to pyrophosphate of the mutant viral reverse transcriptase.

Arion D, Kaushik N, McCormick S, Borkow G, Parniak MA. Arion D, et al. Biochemistry. 1998 Nov 10;37(45):15908-17. doi: 10.1021/bi981200e. Biochemistry. 1998. PMID: 9843396

7

Effect of substituting arabinonucleosides for deoxynucleotides in the DNA priming strand on the polymerase action of HIV-1 RT.

Noronha AM, Arion D, Parniak MA, Damha MJ. Noronha AM, et al. Among authors: arion d. Nucleosides Nucleotides Nucleic Acids. 2001 Apr-Jul;20(4-7):1205-9. doi: 10.1081/NCN-100002520. Nucleosides Nucleotides Nucleic Acids. 2001. PMID: 11562987

8

HIV resistance to zidovudine: the role of pyrophosphorolysis.

Arion D, Parniak MA. Arion D, et al. Drug Resist Updat. 1999 Apr;2(2):91-95. doi: 10.1054/drup.1999.0076. Drug Resist Updat. 1999. PMID: 11504476

9

Mechanism by which phosphonoformic acid resistance mutations restore 3'-azido-3'-deoxythymidine (AZT) sensitivity to AZT-resistant HIV-1 reverse transcriptase.

Arion D, Sluis-Cremer N, Parniak MA. Arion D, et al. J Biol Chem. 2000 Mar 31;275(13):9251-5. doi: 10.1074/jbc.275.13.9251. J Biol Chem. 2000. PMID: 10734063 Free article.

We previously showed that pyrophosphorolytic removal of chain-terminating AZT is the primary mechanism of the AZT resistance phenotype (Arion, D., Kaushik, N., McCormick, S., Borkow, G., and Parniak, M. A. (1998) Biochemistry 37, 15908-15917). ...

We previously showed that pyrophosphorolytic removal of chain-terminating AZT is the primary mechanism of the AZT resistance phenotype (A …

10

Mutational analysis of Lys65 of HIV-1 reverse transcriptase.

Sluis-Cremer N, Arion D, Kaushik N, Lim H, Parniak MA. Sluis-Cremer N, et al. Among authors: arion d. Biochem J. 2000 May 15;348 Pt 1(Pt 1):77-82. Biochem J. 2000. PMID: 10794716 Free PMC article.

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