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First-in-human study of the safety, tolerability, pharmacokinetics, and pharmacodynamics of ALPN-101, a dual CD28/ICOS antagonist, in healthy adult subjects.
Yang J, Lickliter JD, Hillson JL, Means GD, Sanderson RJ, Carley K, Tercero A, Manjarrez KL, Wiley JR, Peng SL. Yang J, et al. Among authors: means gd. Clin Transl Sci. 2021 Jul;14(4):1314-1326. doi: 10.1111/cts.12983. Epub 2021 Mar 2. Clin Transl Sci. 2021. PMID: 33503289 Free PMC article. Clinical Trial.
Aromatase cytochrome P450, the enzyme responsible for estrogen biosynthesis.
Simpson ER, Mahendroo MS, Means GD, Kilgore MW, Hinshelwood MM, Graham-Lorence S, Amarneh B, Ito Y, Fisher CR, Michael MD, et al. Simpson ER, et al. Among authors: means gd. Endocr Rev. 1994 Jun;15(3):342-55. doi: 10.1210/edrv-15-3-342. Endocr Rev. 1994. PMID: 8076586 Review. No abstract available.
Tissue-specific promoters regulate aromatase cytochrome P450 expression.
Simpson ER, Mahendroo MS, Means GD, Kilgore MW, Corbin CJ, Mendelson CR. Simpson ER, et al. Among authors: means gd. J Steroid Biochem Mol Biol. 1993 Mar;44(4-6):321-30. doi: 10.1016/0960-0760(93)90235-o. J Steroid Biochem Mol Biol. 1993. PMID: 8476746 Review.
19 results