Leonard WJ - Search Results

1

Cloning of a receptor subunit required for signaling by thymic stromal lymphopoietin.

Pandey A, Ozaki K, Baumann H, Levin SD, Puel A, Farr AG, Ziegler SF, Leonard WJ, Lodish HF. Pandey A, et al. Among authors: leonard wj. Nat Immunol. 2000 Jul;1(1):59-64. doi: 10.1038/76923. Nat Immunol. 2000. PMID: 10881176

2

Reconstitution of a functional interleukin (IL)-7 receptor demonstrates that the IL-2 receptor gamma chain is required for IL-7 signal transduction.

Ziegler SE, Morella KK, Anderson D, Kumaki N, Leonard WJ, Cosman D, Baumann H. Ziegler SE, et al. Among authors: leonard wj. Eur J Immunol. 1995 Feb;25(2):399-404. doi: 10.1002/eji.1830250214. Eur J Immunol. 1995. PMID: 7875201

3

Heterodimerization of the IL-2 receptor beta- and gamma-chain cytoplasmic domains is required for signalling.

Nakamura Y, Russell SM, Mess SA, Friedmann M, Erdos M, Francois C, Jacques Y, Adelstein S, Leonard WJ. Nakamura Y, et al. Among authors: leonard wj. Nature. 1994 May 26;369(6478):330-3. doi: 10.1038/369330a0. Nature. 1994. PMID: 8183373

4

Interleukin-2 receptor gamma chain: a functional component of the interleukin-7 receptor.

Noguchi M, Nakamura Y, Russell SM, Ziegler SF, Tsang M, Cao X, Leonard WJ. Noguchi M, et al. Among authors: leonard wj. Science. 1993 Dec 17;262(5141):1877-80. doi: 10.1126/science.8266077. Science. 1993. PMID: 8266077

5

Defective IL7R expression in T(-)B(+)NK(+) severe combined immunodeficiency.

Puel A, Ziegler SF, Buckley RH, Leonard WJ. Puel A, et al. Among authors: leonard wj. Nat Genet. 1998 Dec;20(4):394-7. doi: 10.1038/3877. Nat Genet. 1998. PMID: 9843216

6

Mutations in the gene for the IL-7 receptor result in T(-)B(+)NK(+) severe combined immunodeficiency disease.

Puel A, Leonard WJ. Puel A, et al. Among authors: leonard wj. Curr Opin Immunol. 2000 Aug;12(4):468-73. doi: 10.1016/s0952-7915(00)00122-9. Curr Opin Immunol. 2000. PMID: 10899029 Review.

7

Cloning of a type I cytokine receptor most related to the IL-2 receptor beta chain.

Ozaki K, Kikly K, Michalovich D, Young PR, Leonard WJ. Ozaki K, et al. Among authors: leonard wj. Proc Natl Acad Sci U S A. 2000 Oct 10;97(21):11439-44. doi: 10.1073/pnas.200360997. Proc Natl Acad Sci U S A. 2000. PMID: 11016959 Free PMC article.

8

Signaling via the IL-2 and IL-7 receptors from the membrane to the nucleus.

Leonard WJ, Imada K, Nakajima H, Puel A, Soldaini E, John S. Leonard WJ, et al. Cold Spring Harb Symp Quant Biol. 1999;64:417-24. doi: 10.1101/sqb.1999.64.417. Cold Spring Harb Symp Quant Biol. 1999. PMID: 11232316 Review. No abstract available.

9

Cytokine and cytokine receptor pleiotropy and redundancy.

Ozaki K, Leonard WJ. Ozaki K, et al. Among authors: leonard wj. J Biol Chem. 2002 Aug 16;277(33):29355-8. doi: 10.1074/jbc.R200003200. Epub 2002 Jun 18. J Biol Chem. 2002. PMID: 12072446 Free article. Review. No abstract available.

10

A critical role for IL-21 in regulating immunoglobulin production.

Ozaki K, Spolski R, Feng CG, Qi CF, Cheng J, Sher A, Morse HC 3rd, Liu C, Schwartzberg PL, Leonard WJ. Ozaki K, et al. Among authors: leonard wj. Science. 2002 Nov 22;298(5598):1630-4. doi: 10.1126/science.1077002. Science. 2002. PMID: 12446913

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