Chapman GA - Search Results

1

Fractalkine cleavage from neuronal membranes represents an acute event in the inflammatory response to excitotoxic brain damage.

Chapman GA, Moores K, Harrison D, Campbell CA, Stewart BR, Strijbos PJ. Chapman GA, et al. J Neurosci. 2000 Aug 1;20(15):RC87. doi: 10.1523/JNEUROSCI.20-15-j0004.2000. J Neurosci. 2000. PMID: 10899174 Free PMC article.

2

The role of fractalkine in the recruitment of monocytes to the endothelium.

Chapman GA, Moores KE, Gohil J, Berkhout TA, Patel L, Green P, Macphee CH, Stewart BR. Chapman GA, et al. Eur J Pharmacol. 2000 Mar 31;392(3):189-95. doi: 10.1016/s0014-2999(00)00117-5. Eur J Pharmacol. 2000. PMID: 10762673

3

Fractalkine is expressed by smooth muscle cells in response to IFN-gamma and TNF-alpha and is modulated by metalloproteinase activity.

Ludwig A, Berkhout T, Moores K, Groot P, Chapman G. Ludwig A, et al. J Immunol. 2002 Jan 15;168(2):604-12. doi: 10.4049/jimmunol.168.2.604. J Immunol. 2002. PMID: 11777952

4

Site-specific splice variation of the human P2X4 receptor.

Carpenter D, Meadows HJ, Brough S, Chapman G, Clarke C, Coldwell M, Davis R, Harrison D, Meakin J, McHale M, Rice SQ, Tomlinson WJ, Wood M, Sanger GJ. Carpenter D, et al. Neurosci Lett. 1999 Oct 8;273(3):183-6. doi: 10.1016/s0304-3940(99)00653-9. Neurosci Lett. 1999. PMID: 10515189

5

Evidence that exogenous and endogenous fractalkine can induce spinal nociceptive facilitation in rats.

Milligan ED, Zapata V, Chacur M, Schoeniger D, Biedenkapp J, O'Connor KA, Verge GM, Chapman G, Green P, Foster AC, Naeve GS, Maier SF, Watkins LR. Milligan ED, et al. Eur J Neurosci. 2004 Nov;20(9):2294-302. doi: 10.1111/j.1460-9568.2004.03709.x. Eur J Neurosci. 2004. PMID: 15525271

6

ASP1 (BACE2) cleaves the amyloid precursor protein at the beta-secretase site.

Hussain I, Powell DJ, Howlett DR, Chapman GA, Gilmour L, Murdock PR, Tew DG, Meek TD, Chapman C, Schneider K, Ratcliffe SJ, Tattersall D, Testa TT, Southan C, Ryan DM, Simmons DL, Walsh FS, Dingwall C, Christie G. Hussain I, et al. Among authors: chapman c, chapman ga. Mol Cell Neurosci. 2000 Nov;16(5):609-19. doi: 10.1006/mcne.2000.0884. Mol Cell Neurosci. 2000. PMID: 11083922

7

Identification and structure-activity relationships of 1-aryl-3-piperidin-4-yl-urea derivatives as CXCR3 receptor antagonists.

Allen DR, Bolt A, Chapman GA, Knight RL, Meissner JW, Owen DA, Watson RJ. Allen DR, et al. Among authors: chapman ga. Bioorg Med Chem Lett. 2007 Feb 1;17(3):697-701. doi: 10.1016/j.bmcl.2006.10.088. Epub 2006 Nov 2. Bioorg Med Chem Lett. 2007. PMID: 17097877

8

Development of CXCR3 antagonists. Part 2: Identification of 2-amino(4-piperidinyl)azoles as potent CXCR3 antagonists.

Watson RJ, Allen DR, Birch HL, Chapman GA, Hannah DR, Knight RL, Meissner JW, Owen DA, Thomas EJ. Watson RJ, et al. Among authors: chapman ga. Bioorg Med Chem Lett. 2007 Dec 15;17(24):6806-10. doi: 10.1016/j.bmcl.2007.10.029. Epub 2007 Oct 17. Bioorg Med Chem Lett. 2007. PMID: 17964154

9

Development of CXCR3 antagonists. Part 3: Tropenyl and homotropenyl-piperidine urea derivatives.

Watson RJ, Allen DR, Birch HL, Chapman GA, Galvin FC, Jopling LA, Knight RL, Meier D, Oliver K, Meissner JW, Owen DA, Thomas EJ, Tremayne N, Williams SC. Watson RJ, et al. Among authors: chapman ga. Bioorg Med Chem Lett. 2008 Jan 1;18(1):147-51. doi: 10.1016/j.bmcl.2007.10.109. Epub 2007 Nov 4. Bioorg Med Chem Lett. 2008. PMID: 18032038

10

Development of CXCR3 antagonists. Part 4: discovery of 2-amino-(4-tropinyl)quinolines.

Knight RL, Allen DR, Birch HL, Chapman GA, Galvin FC, Jopling LA, Lock CJ, Meissner JW, Owen DA, Raphy G, Watson RJ, Williams SC. Knight RL, et al. Among authors: chapman ga. Bioorg Med Chem Lett. 2008 Jan 15;18(2):629-33. doi: 10.1016/j.bmcl.2007.11.075. Epub 2007 Nov 28. Bioorg Med Chem Lett. 2008. PMID: 18068363

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