Jack C - Search Results

1

Aspartate mutations in presenilin and gamma-secretase inhibitors both impair notch1 proteolysis and nuclear translocation with relative preservation of notch1 signaling.

Berezovska O, Jack C, McLean P, Aster JC, Hicks C, Xia W, Wolfe MS, Kimberly WT, Weinmaster G, Selkoe DJ, Hyman BT. Berezovska O, et al. Among authors: jack c. J Neurochem. 2000 Aug;75(2):583-93. doi: 10.1046/j.1471-4159.2000.0750583.x. J Neurochem. 2000. PMID: 10899933 Free article.

2

Gamma-secretase/presenilin inhibitors for Alzheimer's disease phenocopy Notch mutations in Drosophila.

Micchelli CA, Esler WP, Kimberly WT, Jack C, Berezovska O, Kornilova A, Hyman BT, Perrimon N, Wolfe MS. Micchelli CA, et al. Among authors: jack c. FASEB J. 2003 Jan;17(1):79-81. doi: 10.1096/fj.02-0394fje. Epub 2002 Nov 1. FASEB J. 2003. PMID: 12424225

3

Rapid Notch1 nuclear translocation after ligand binding depends on presenilin-associated gamma-secretase activity.

Berezovska O, Jack C, McLean P, Aster JC, Hicks C, Xia W, Wolfe MS, Weinmaster G, Selkoe DJ, Hyman BT. Berezovska O, et al. Among authors: jack c. Ann N Y Acad Sci. 2000;920:223-6. doi: 10.1111/j.1749-6632.2000.tb06926.x. Ann N Y Acad Sci. 2000. PMID: 11193154

4

Effect of PS1 deficiency and an APP gamma-secretase inhibitor on Notch1 signaling in primary mammalian neurons.

Jack C, Berezovska O, Wolfe MS, Hyman BT. Jack C, et al. Brain Res Mol Brain Res. 2001 Mar 5;87(2):166-74. doi: 10.1016/s0169-328x(01)00010-9. Brain Res Mol Brain Res. 2001. PMID: 11245918

5

Notch1 and amyloid precursor protein are competitive substrates for presenilin1-dependent gamma-secretase cleavage.

Berezovska O, Jack C, Deng A, Gastineau N, Rebeck GW, Hyman BT. Berezovska O, et al. Among authors: jack c. J Biol Chem. 2001 Aug 10;276(32):30018-23. doi: 10.1074/jbc.M008268200. Epub 2001 Jun 14. J Biol Chem. 2001. PMID: 11408475 Free article.

6

Predicting cognitive decline from neuropsychiatric symptoms and Alzheimer's disease biomarkers: A machine learning approach to a population-based data.

Shah J, Krell-Roesch J, Forzani E, Knopman DS, Jack CR, Petersen RC, Che Y, Wu T, Geda YE. Shah J, et al. Among authors: jack cr. J Alzheimers Dis. 2025 Jan 10:13872877241306654. doi: 10.1177/13872877241306654. Online ahead of print. J Alzheimers Dis. 2025. PMID: 39791216

7

Integrative multiomics reveals common endotypes across PSEN1, PSEN2, and APP mutations in familial Alzheimer's disease.

Valdes P, Caldwell AB, Liu Q, Fitzgerald MQ, Ramachandran S, Karch CM; Dominantly Inherited Alzheimer Network (DIAN); Galasko DR, Yuan SH, Wagner SL, Subramaniam S. Valdes P, et al. Alzheimers Res Ther. 2025 Jan 4;17(1):5. doi: 10.1186/s13195-024-01659-6. Alzheimers Res Ther. 2025. PMID: 39754192 Free PMC article.

8

Application of the revised criteria for diagnosis and staging of Alzheimer's disease: Drug development and clinical practice.

Jack CR, Graf A, Burnham SC, Doty EG, Moebius HJ, Montenigro P, Siemers E, Sink KM, Shaw LM, Hansen CT, Wildsmith KR, Mahinrad S, Carrillo MC, Weber CJ. Jack CR, et al. Alzheimers Dement (N Y). 2024 Dec 14;10(4):e70013. doi: 10.1002/trc2.70013. eCollection 2024 Oct-Dec. Alzheimers Dement (N Y). 2024. PMID: 39748835 Free PMC article.

9

Real-Time 2D Phase-Contrast MRI to Assess Cardiac- and Respiratory-Driven CSF Movement in Normal Pressure Hydrocephalus.

Karki P, Murphy MC, Ganji S, Gunter JL, Graff-Radford J, Jones DT, Botha H, Cutsforth-Gregory JK, Elder BD, Jack CR Jr, Huston J 3rd, Cogswell PM. Karki P, et al. Among authors: jack cr jr. J Neuroimaging. 2025 Jan-Feb;35(1):e70000. doi: 10.1111/jon.70000. J Neuroimaging. 2025. PMID: 39737803 Free PMC article.

10

Microstructural mapping of neural pathways in Alzheimer's disease using macrostructure-informed normative tractometry.

Feng Y, Chandio BQ, Villalon-Reina JE, Thomopoulos SI, Nir TM, Benavidez S, Laltoo E, Chattopadhyay T, Joshi H, Venkatasubramanian G, John JP, Jahanshad N, Reid RI, Jack CR, Weiner MW, Thompson PM; Alzheimer's Disease Neuroimaging Initiative. Feng Y, et al. Among authors: jack cr. Alzheimers Dement. 2024 Dec 30. doi: 10.1002/alz.14371. Online ahead of print. Alzheimers Dement. 2024. PMID: 39737627

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