McLean P - Search Results

1

Aspartate mutations in presenilin and gamma-secretase inhibitors both impair notch1 proteolysis and nuclear translocation with relative preservation of notch1 signaling.

Berezovska O, Jack C, McLean P, Aster JC, Hicks C, Xia W, Wolfe MS, Kimberly WT, Weinmaster G, Selkoe DJ, Hyman BT. Berezovska O, et al. Among authors: mclean p. J Neurochem. 2000 Aug;75(2):583-93. doi: 10.1046/j.1471-4159.2000.0750583.x. J Neurochem. 2000. PMID: 10899933 Free article.

2

Interaction of alpha-synuclein and synphilin-1: effect of Parkinson's disease-associated mutations.

Kawamata H, McLean PJ, Sharma N, Hyman BT. Kawamata H, et al. Among authors: mclean pj. J Neurochem. 2001 May;77(3):929-34. doi: 10.1046/j.1471-4159.2001.00301.x. J Neurochem. 2001. PMID: 11331421 Free article.

3

Notch1 inhibits neurite outgrowth in postmitotic primary neurons.

Berezovska O, McLean P, Knowles R, Frosh M, Lu FM, Lux SE, Hyman BT. Berezovska O, et al. Among authors: mclean p. Neuroscience. 1999;93(2):433-9. doi: 10.1016/s0306-4522(99)00157-8. Neuroscience. 1999. PMID: 10465425

4

Rapid Notch1 nuclear translocation after ligand binding depends on presenilin-associated gamma-secretase activity.

Berezovska O, Jack C, McLean P, Aster JC, Hicks C, Xia W, Wolfe MS, Weinmaster G, Selkoe DJ, Hyman BT. Berezovska O, et al. Among authors: mclean p. Ann N Y Acad Sci. 2000;920:223-6. doi: 10.1111/j.1749-6632.2000.tb06926.x. Ann N Y Acad Sci. 2000. PMID: 11193154

5

An alternatively spliced form of rodent alpha-synuclein forms intracellular inclusions in vitro: role of the carboxy-terminus in alpha-synuclein aggregation.

McLean PJ, Hyman BT. McLean PJ, et al. Neurosci Lett. 2002 May 3;323(3):219-23. doi: 10.1016/s0304-3940(02)00154-4. Neurosci Lett. 2002. PMID: 11959424

6

TorsinA and heat shock proteins act as molecular chaperones: suppression of alpha-synuclein aggregation.

McLean PJ, Kawamata H, Shariff S, Hewett J, Sharma N, Ueda K, Breakefield XO, Hyman BT. McLean PJ, et al. J Neurochem. 2002 Nov;83(4):846-54. doi: 10.1046/j.1471-4159.2002.01190.x. J Neurochem. 2002. PMID: 12421356 Free article.

7

Comparison of transduction efficiency of recombinant AAV serotypes 1, 2, 5, and 8 in the rat nigrostriatal system.

McFarland NR, Lee JS, Hyman BT, McLean PJ. McFarland NR, et al. J Neurochem. 2009 May;109(3):838-45. doi: 10.1111/j.1471-4159.2009.06010.x. Epub 2009 Feb 24. J Neurochem. 2009. PMID: 19250335 Free PMC article.

8

Alpha-synuclein-enhanced green fluorescent protein fusion proteins form proteasome sensitive inclusions in primary neurons.

McLean PJ, Kawamata H, Hyman BT. McLean PJ, et al. Neuroscience. 2001;104(3):901-12. doi: 10.1016/s0306-4522(01)00113-0. Neuroscience. 2001. PMID: 11440819

9

The Alzheimer-related gene presenilin 1 facilitates notch 1 in primary mammalian neurons.

Berezovska O, Frosch M, McLean P, Knowles R, Koo E, Kang D, Shen J, Lu FM, Lux SE, Tonegawa S, Hyman BT. Berezovska O, et al. Among authors: mclean p. Brain Res Mol Brain Res. 1999 Jun 8;69(2):273-80. doi: 10.1016/s0169-328x(99)00119-9. Brain Res Mol Brain Res. 1999. PMID: 10366748

10

Dopaminergic neuron loss and up-regulation of chaperone protein mRNA induced by targeted over-expression of alpha-synuclein in mouse substantia nigra.

St Martin JL, Klucken J, Outeiro TF, Nguyen P, Keller-McGandy C, Cantuti-Castelvetri I, Grammatopoulos TN, Standaert DG, Hyman BT, McLean PJ. St Martin JL, et al. Among authors: mclean pj. J Neurochem. 2007 Mar;100(6):1449-57. doi: 10.1111/j.1471-4159.2006.04310.x. Epub 2007 Jan 4. J Neurochem. 2007. PMID: 17241127 Free article.

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