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Aspartate mutations in presenilin and gamma-secretase inhibitors both impair notch1 proteolysis and nuclear translocation with relative preservation of notch1 signaling.
Berezovska O, Jack C, McLean P, Aster JC, Hicks C, Xia W, Wolfe MS, Kimberly WT, Weinmaster G, Selkoe DJ, Hyman BT. Berezovska O, et al. Among authors: weinmaster g. J Neurochem. 2000 Aug;75(2):583-93. doi: 10.1046/j.1471-4159.2000.0750583.x. J Neurochem. 2000. PMID: 10899933 Free article.
Notch receptor activation inhibits oligodendrocyte differentiation.
Wang S, Sdrulla AD, diSibio G, Bush G, Nofziger D, Hicks C, Weinmaster G, Barres BA. Wang S, et al. Among authors: weinmaster g. Neuron. 1998 Jul;21(1):63-75. doi: 10.1016/s0896-6273(00)80515-2. Neuron. 1998. PMID: 9697852 Free article.
CADASIL Notch3 mutant proteins localize to the cell surface and bind ligand.
Haritunians T, Boulter J, Hicks C, Buhrman J, DiSibio G, Shawber C, Weinmaster G, Nofziger D, Schanen C. Haritunians T, et al. Among authors: weinmaster g. Circ Res. 2002 Mar 22;90(5):506-8. doi: 10.1161/01.res.0000013796.73742.c8. Circ Res. 2002. PMID: 11909813 Free PMC article.
88 results