Xia W - Search Results

1

Aspartate mutations in presenilin and gamma-secretase inhibitors both impair notch1 proteolysis and nuclear translocation with relative preservation of notch1 signaling.

Berezovska O, Jack C, McLean P, Aster JC, Hicks C, Xia W, Wolfe MS, Kimberly WT, Weinmaster G, Selkoe DJ, Hyman BT. Berezovska O, et al. Among authors: xia w. J Neurochem. 2000 Aug;75(2):583-93. doi: 10.1046/j.1471-4159.2000.0750583.x. J Neurochem. 2000. PMID: 10899933 Free article.

2

Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice.

Citron M, Westaway D, Xia W, Carlson G, Diehl T, Levesque G, Johnson-Wood K, Lee M, Seubert P, Davis A, Kholodenko D, Motter R, Sherrington R, Perry B, Yao H, Strome R, Lieberburg I, Rommens J, Kim S, Schenk D, Fraser P, St George Hyslop P, Selkoe DJ. Citron M, et al. Among authors: xia w. Nat Med. 1997 Jan;3(1):67-72. doi: 10.1038/nm0197-67. Nat Med. 1997. PMID: 8986743

3

Enhanced production and oligomerization of the 42-residue amyloid beta-protein by Chinese hamster ovary cells stably expressing mutant presenilins.

Xia W, Zhang J, Kholodenko D, Citron M, Podlisny MB, Teplow DB, Haass C, Seubert P, Koo EH, Selkoe DJ. Xia W, et al. J Biol Chem. 1997 Mar 21;272(12):7977-82. doi: 10.1074/jbc.272.12.7977. J Biol Chem. 1997. PMID: 9065468 Free article.

4

Skeletal and CNS defects in Presenilin-1-deficient mice.

Shen J, Bronson RT, Chen DF, Xia W, Selkoe DJ, Tonegawa S. Shen J, et al. Among authors: xia w. Cell. 1997 May 16;89(4):629-39. doi: 10.1016/s0092-8674(00)80244-5. Cell. 1997. PMID: 9160754 Free article.

5

Presenilin proteins undergo heterogeneous endoproteolysis between Thr291 and Ala299 and occur as stable N- and C-terminal fragments in normal and Alzheimer brain tissue.

Podlisny MB, Citron M, Amarante P, Sherrington R, Xia W, Zhang J, Diehl T, Levesque G, Fraser P, Haass C, Koo EH, Seubert P, St George-Hyslop P, Teplow DB, Selkoe DJ. Podlisny MB, et al. Among authors: xia w. Neurobiol Dis. 1997;3(4):325-37. doi: 10.1006/nbdi.1997.0129. Neurobiol Dis. 1997. PMID: 9173929

6

Interaction between amyloid precursor protein and presenilins in mammalian cells: implications for the pathogenesis of Alzheimer disease.

Xia W, Zhang J, Perez R, Koo EH, Selkoe DJ. Xia W, et al. Proc Natl Acad Sci U S A. 1997 Jul 22;94(15):8208-13. doi: 10.1073/pnas.94.15.8208. Proc Natl Acad Sci U S A. 1997. PMID: 9223340 Free PMC article.

7

A substrate-based difluoro ketone selectively inhibits Alzheimer's gamma-secretase activity.

Wolfe MS, Citron M, Diehl TS, Xia W, Donkor IO, Selkoe DJ. Wolfe MS, et al. Among authors: xia w. J Med Chem. 1998 Jan 1;41(1):6-9. doi: 10.1021/jm970621b. J Med Chem. 1998. PMID: 9438016 No abstract available.

8

Subcellular distribution and turnover of presenilins in transfected cells.

Zhang J, Kang DE, Xia W, Okochi M, Mori H, Selkoe DJ, Koo EH. Zhang J, et al. Among authors: xia w. J Biol Chem. 1998 May 15;273(20):12436-42. doi: 10.1074/jbc.273.20.12436. J Biol Chem. 1998. PMID: 9575200 Free article.

9

Lack of specific association of presenilin 1 (PS-1) protein with plaques and tangles in Alzheimer's disease.

Xia MQ, Berezovska O, Kim TW, Xia WM, Liao A, Tanzi RE, Selkoe D, Hyman BT. Xia MQ, et al. Among authors: xia wm. J Neurol Sci. 1998 Jun 11;158(1):15-23. doi: 10.1016/s0022-510x(98)00106-3. J Neurol Sci. 1998. PMID: 9667772

10

Additive effects of PS1 and APP mutations on secretion of the 42-residue amyloid beta-protein.

Citron M, Eckman CB, Diehl TS, Corcoran C, Ostaszewski BL, Xia W, Levesque G, St George Hyslop P, Younkin SG, Selkoe DJ. Citron M, et al. Among authors: xia w. Neurobiol Dis. 1998 Aug;5(2):107-16. doi: 10.1006/nbdi.1998.0183. Neurobiol Dis. 1998. PMID: 9746908

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

5,412 results

Search Page

Filters