Morphine peripheral analgesia depends on activation of the PI3Kgamma/AKT/nNOS/NO/KATP signaling pathway.
Cunha TM, Roman-Campos D, Lotufo CM, Duarte HL, Souza GR, Verri WA Jr, Funez MI, Dias QM, Schivo IR, Domingues AC, Sachs D, Chiavegatto S, Teixeira MM, Hothersall JS, Cruz JS, Cunha FQ, Ferreira SH.
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Proc Natl Acad Sci U S A. 2010 Mar 2;107(9):4442-7. doi: 10.1073/pnas.0914733107. Epub 2010 Feb 10.
Proc Natl Acad Sci U S A. 2010.
PMID: 20147620
Free PMC article.